journal article·2026-02

Magnetic hyperthermia-induced hydrogen therapy for cancer treatment using PEG-coated Mg–Ni Degradable microrobots

Sourav Dutta, Tanushree Patra, Kyungmoo Yea, Hongsoo Choi

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OpenAlex topics: Micro and Nano Robotics · Hydrogen's biological and therapeutic effects · Nanoplatforms for cancer theranostics

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References (71)

Show source-provided references
1. Magnetically manipulated optoelectronic hybrid microrobots for optically targeted non-genetic neuromodulation
2. Engineering microrobots for targeted cancer therapies from a medical perspective10.1038/s41467-020-19322-7 ↗
3. A magnetically powered stem cell-based microrobot for minimally invasive stem cell delivery via the intranasal pathway in a mouse brain
4. Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism10.1126/scitranslmed.aan0026 ↗
5. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models10.1038/s41556-018-0256-3 ↗
6. Self-assembly of an amphiphilic Janus camptothecin-floxuridine conjugate into liposome-like nanocapsules for more efficacious combination chemotherapy in cancer10.1002/adma.201703135 ↗
7. Magnesium-based micromotors for enhanced active and synergistic hydrogen chemotherapy
8. Advances of medical nanorobots for future cancer treatments10.1186/s13045-023-01463-z ↗
9. Intelligent micro-/nanorobots for cancer Theragnostic
10. 3D Printed enzymatically biodegradable soft helical microswimmers
11. Recent developments in metallic degradable micromotors for biomedical and environmental remediation applications10.1007/s40820-023-01259-3 ↗
12. ROS homeostasis and metabolism: a dangerous liason in cancer cells10.1038/cddis.2016.105 ↗
13. ROS in cancer therapy: the bright side of the moon10.1038/s12276-020-0384-2 ↗
14. A near-infrared-II fluorescent nanoprobe offering real-time tracking of fenton-like reaction for cancer chemodynamic theranostics10.1021/acs.nanolett.4c05087 ↗
15. Modulating ROS to overcome multidrug resistance in cancer10.1016/j.drup.2018.11.001 ↗
16. Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment10.1016/j.addr.2020.06.006 ↗
17. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?10.1038/nrd2803 ↗
18. ROS homeostasis and metabolism: a critical liaison for cancer therapy10.1038/emm.2016.119 ↗
19. Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth10.1038/s41467-022-29938-6 ↗
20. Novel gas-based nanomedicines for cancer therapy10.1002/VIW.20200185 ↗
21. Gas-generating nanoplatforms: material chemistry, multifunctionality, and Gas therapy10.1002/adma.201801964 ↗
22. Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS10.1038/s41467-020-14413-x ↗
23. Situ nanoreactor for photosynthesizing H2 gas to mitigate oxidative stress in tissue inflammation10.1021/jacs.7b07492 ↗
24. Molecular hydrogen: a potential radioprotective agent10.1016/j.biopha.2020.110589 ↗
25. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals10.1038/nm1577 ↗
26. Neuroprotective effect of hydrogen-rich saline in global cerebral ischemia/reperfusion rats: up-regulated tregs and down-regulated miR-21, miR-210 and NF-κb expression10.1007/s11064-016-1978-x ↗
27. Hydrogen gas from inflammation treatment to cancer therapy10.1021/acsnano.9b05124 ↗
28. Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis
29. Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice10.1038/oby.2011.6 ↗
30. Zn-Fe primary battery-enabled controlled hydrogen release in stomach for improving insulin resistance in obesity-associated type 2 diabetes
31. Injectable spontaneous hydrogen-releasing hydrogel for long-lasting alleviation of osteoarthritis10.1016/j.actbio.2022.12.056 ↗
32. The role of hydrogen therapy in Alzheimer’s disease management: insights into mechanisms, administration routes, and future challenges10.1016/j.biopha.2023.115807 ↗
33. Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice10.1016/j.jneuroim.2016.03.006 ↗
34. Strategies for engineering advanced nanomedicines for gas therapy of cancer10.1093/nsr/nwaa034 ↗
35. Molecular Hydrogen therapy: mechanisms, delivery methods, preventive, and therapeutic application10.1002/mco2.70194 ↗
36. Hydrogen: a rising star in gas medicine as a mitochondria-targeting nutrient via activating Keap1-Nrf2 antioxidant system10.3390/antiox12122062 ↗
37. Hydrogen protects mitochondrial function by increasing the expression of PGC-1α and ameliorating myocardial ischaemia–Reperfusion injury10.1111/jcmm.70236 ↗
38. ONOOH does not react with H2: potential beneficial effects of H2 as an antioxidant by selective reaction with hydroxyl radicals and peroxynitrite10.1016/j.freeradbiomed.2014.07.025 ↗
39. A green, efficient and precise hydrogen therapy of cancer based on in vivo electrochemistry10.1093/nsr/nwz199 ↗
40. Acid-responsive H2-releasing 2D MgB2 nanosheet for therapeutic synergy and side effect attenuation of gastric cancer chemotherapy
41. Acid-responsive H2-releasing Fe nanoparticles for safe and effective cancer therapy10.1039/C9TB00338J ↗
42. Porphyrin–palladium hydride MOF nanoparticles for tumor-targeting photoacoustic imaging-guided hydrogenothermal cancer therapy10.1039/C9NH00021F ↗
43. Palladium hydride nanopocket cubes and their H2-therapy function in amplifying inhibition of foam cells to attenuate atherosclerosis10.1002/adfm.202104892 ↗
44. Magnesium biomaterials for orthopedic application: a review from a biological perspective10.1002/jbm.b.33113 ↗
45. Micromotors for active delivery of minerals toward the treatment of iron deficiency anemia10.1021/acs.nanolett.9b02832 ↗
46. Magnesium biomaterials for orthopedic application: a review from a biological perspective10.1002/jbm.b.33113 ↗
47. Magnesium and its alloys as orthopedic biomaterials: a review10.1016/j.biomaterials.2005.10.003 ↗
48. Recent developments in magnesium metal–Matrix composites for biomedical applications: a review10.1021/acsbiomaterials.0c00678 ↗
49. Micromotor-enabled active drug delivery for in vivo treatment of stomach infection10.1038/s41467-017-00309-w ↗
50. Magnetically coated bioabsorbable stents for renormalization of arterial vessel walls after stent implantation10.1021/acs.nanolett.7b04096 ↗
51. Magnesium-based micromotors as hydrogen generators for precise rheumatoid arthritis therapy10.1021/acs.nanolett.0c04438 ↗
52. Self-propelled Janus micromotors for pH-responsive release of small molecule drug
53. Biomimetic micromotor enables active delivery of antigens for oral vaccination10.1021/acs.nanolett.8b05051 ↗
54. Magnetically actuated degradable microrobots for actively controlled drug release and hyperthermia therapy10.1002/adhm.201900213 ↗
55. Closed-loop temperature-controlled magnetic hyperthermia therapy with magnetic guidance of superparamagnetic iron-oxide nanoparticles10.1002/adtp.202100237 ↗
56. Low-melting-point polymeric nanoshells for thermal-triggered drug release under hyperthermia condition10.3109/02656736.2015.1094147 ↗
57. Derivation of an oral toxicity reference value for nickel10.1016/j.yrtph.2017.03.011 ↗
58. Biomimetic hydrogel coatings for improving the corrosion resistance, hemocompatibility, and endothelial cell growth of the magnesium alloy10.1016/j.colsurfb.2024.114204 ↗
59. In vitro corrosion and cytocompatibility studies of hot press sintered magnesium-bioactive glass composite10.1016/j.mtla.2019.100245 ↗
60. Green” gas-generation strategy to combine cancer phototherapy for remarkably enhanced efficacy10.1016/j.ntm.2025.100090 ↗
61. Reactive oxygen species: multidimensional regulators of plant adaptation to abiotic stress and development10.1111/jipb.13601 ↗
62. Feature-guided clustering of multi-dimensional flow cytometry datasets10.1016/j.jbi.2006.06.005 ↗
63. Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease10.1016/j.biopha.2024.116802 ↗
64. The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: a randomized controlled study10.1016/j.freeradbiomed.2024.07.010 ↗
65. Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway10.1186/s12885-019-6491-6 ↗
66. Magnesium alloys in tumor treatment: current research status, challenges and future prospects10.1016/j.jma.2023.08.008 ↗
67. Multifunctional magnesium anastomosis staples for wound closure and inhibition of tumor recurrence and metastasis10.1021/acsbiomaterials.1c00683 ↗
68. Magnesium metal and its corrosion products: promising materials for tumor interventional therapy10.1016/j.jma.2023.02.007 ↗
69. Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels10.1074/jbc.M112.393918 ↗
70. Magnesium and microvascular endothelial cells: a role in inflammation and angiogenesis10.2741/1610 ↗
71. Molecular hydrogen: a therapeutic antioxidant and beyond10.4103/2045-9912.196904 ↗