journal article·2022-03

Microenvironment-activatable cascaded responsive carbonized polymer dots as a theranostic platform for precise rapamycin delivery to potentiate the synergy of chemotherapy and γδ T cells-mediated immunotherapy against tumor

Hua Zhang, Haijie Zhao, Yan Huang, Guodong Sun, Yi Zhang

Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Immune Cell Function and Interaction · Nanoplatforms for cancer theranostics · Immunotherapy and Immune Responses

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (45)

Show source-provided references
1. Emerging concepts for immune checkpoint blockade-based combination therapies10.1016/j.ccell.2018.03.005 ↗
2. Chimeric antigen receptor therapy for cancer10.1146/annurev-med-060512-150254 ↗
3. γδT cells–Pleiotropic immune effectors with therapeutic potential in cancer10.1038/s41568-019-0153-5 ↗
4. γδT cells–First line of defense and beyond10.1146/annurev-immunol-032713-120216 ↗
5. The multifunctionality of human Vγ9Vδ2 γδT cells–Clonal plasticity or distinct subsets?10.1111/j.1365-3083.2012.02727.x ↗
6. Role of gamma-delta (γδ) T cells in autoimmunity10.1189/jlb.3RU0914-443R ↗
7. The role of the γδT cell in allergic diseases10.1155/2014/963484 ↗
8. Gamma-delta (γδ) T cells–Friend or foe in cancer development?10.1186/s12967-017-1378-2 ↗
9. Lysis of a broad range of epithelial tumour cells by human γδT cells–Involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition10.1111/j.1365-3083.2007.01963.x ↗
10. Regulation of ligands for the NKG2D activating receptor10.1146/annurev-immunol-032712-095951 ↗
11. Roles of the NKG2D immunoreceptor and its ligands10.1038/nri1199 ↗
12. Advances in NKG2D ligand recognition and responses by NK cells10.1038/icb.2013.111 ↗
13. mTOR inhibition potentiates cytotoxicity of Vγ4 γδT cells via up-regulating NKG2D and TNF-α10.1189/jlb.5A0116-053RR ↗
14. mTOR-targeted therapy of cancer with rapamycin derivatives10.1093/annonc/mdi113 ↗
15. Cancer nanomedicine for combination cancer immunotherapy10.1038/s41578-019-0108-1 ↗
16. Augmenting the synergies of chemotherapy and immunotherapy through drug delivery10.1016/j.actbio.2019.02.012 ↗
17. Highly integrated nano-platform for breaking the barrier between chemotherapy and immunotherapy10.1021/acs.nanolett.6b01432 ↗
18. Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy10.1038/s41401-020-0400-z ↗
19. Nanoparticle-mediated immunogenic cell death enables and potentiates cancer immunotherapy10.1002/anie.201804882 ↗
20. Rational design of cancer nanomedicine–Nanoproperty integration and synchronization
21. Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy10.1021/acs.chemrev.5b00148 ↗
22. Carbon dots for in vivo bioimaging and theranostics10.1002/smll.201805087 ↗
23. Evolution and synthesis of carbon dots–From carbon dots to carbonized polymer dots10.1002/advs.201901316 ↗
24. Microenvironment-driven cascaded responsive hybrid carbon dots as a multifunctional theranostic nanoplatform for imaging-traceable gene precise delivery10.1021/acs.chemmater.8b01011 ↗
25. Progress in internal/external stimuli responsive fluorescent carbon nanoparticles for theranostic and sensing applications10.1039/C7TB03323K ↗
26. Enzyme-activatable polymer-drug conjugate augments tumour penetration and treatment efficacy10.1038/s41565-019-0485-z ↗
27. Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione10.1016/j.carbon.2016.04.003 ↗
28. Resolving the multiple emission centers in carbon dots–From fluorophore molecular states to aromatic domain states and carbon-core states10.1021/acs.jpclett.8b02043 ↗
29. Charge-convertible carbon dots for imaging guided drug delivery with enhanced in vivo cancer therapeutic efficiency10.1021/acsnano.6b00043 ↗
30. Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy
31. The effect of particle design on cellular internalization pathways10.1073/pnas.0801763105 ↗
32. CD44-targeted hyaluronic acid-coated redox-responsive hyperbranched poly(amido amine)/plasmid DNA ternary nanoassemblies for efficient gene delivery10.1021/acs.bioconjchem.6b00240 ↗
33. Effects of Cremophor EL/ethanol/oleinic acid/water microemulsion on human blood components and coagulation function10.1016/j.colsurfb.2019.04.058 ↗
34. Polyethylenimine-induced alterations of red blood cells and their recognition by the complement system and macrophages10.1021/ab500128q ↗
35. Self-sensibilized polymeric prodrug co-delivering MMP-9 shRNA plasmid for combined treatment of tumors10.1016/j.actbio.2018.01.014 ↗
36. mTOR signaling in growth, metabolism, and disease10.1016/j.cell.2017.03.035 ↗
37. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling10.1074/jbc.M803348200 ↗
38. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control10.1016/S1097-2765(02)00636-6 ↗
39. Innate immune recognition of cancer10.1146/annurev-immunol-032414-112043 ↗
40. Dendritic cell SIRT1-HIF1alpha axis programs the differentiation of CD4+ T cells through IL-12 and TGF-beta1
41. Naturally activated Vγ4 γδT cells play a protective role in tumor immunity through expression of eomesodermin10.4049/jimmunol.0903767 ↗
42. ΓδT cells and the lymphoid stress-surveillance response10.1016/j.immuni.2009.08.006 ↗
43. Identification and characterization of latency-associated peptide-expressing γδT cells10.1038/ncomms9726 ↗
44. Natural plant-derived polygalacturonic acid-oleanolic acid assemblies as oral-delivered nanomedicine for insulin resistance treatment
45. Baicalin alleviates lipopolysaccharide-induced liver inflammation in chicken by suppressing TLR4-mediated NF- κB Pathway10.3389/fphar.2017.00547 ↗