Role of miR-21-5p in the protective effects of PLGA-encapsulated extracellular vesicles from urine-derived stem cells on periprosthetic osteolysis
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Abstract
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Research context
OpenAlex topics: Extracellular vesicles in disease · Bone fractures and treatments · Bone Tissue Engineering Materials
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References (49)
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1. Periprosthetic osteolysis: mechanisms, prevention and treatment10.3390/jcm8122091 ↗
2. Osteolysis around total knee arthroplasty: a review of pathogenetic mechanisms10.1016/j.actbio.2013.05.005 ↗
3. Recent advances in total joint replacement10.1002/jor.24734 ↗
4. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up10.1016/S0140-6736(18)32531-5 ↗
5. Long-term survivorship of total hip arthroplasty with highly cross-linked polyethylene for osteonecrosis10.2106/JBJS.18.01218 ↗
6. Particle disease really does exist10.1080/17453674.2017.1402463 ↗
7. Osteolysis: basic science10.1097/00003086-200112000-00008 ↗
8. Introduction to stem cells and regenerative medicine10.1159/000345615 ↗
9. Stem cells: roadmap to the clinic10.1172/JCI41801 ↗
10. Developmental Committee of the European Group for Blood and Marrow Transplantation. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study10.1016/S0140-6736(08)60690-X ↗
11. Immunomodulatory effect of mesenchymal stromal cells: possible mechanisms10.2217/17460751.3.4.531 ↗
12. Urine-derived stem cells: applications in regenerative and predictive medicine10.3390/cells9030573 ↗
13. Adult stem cell-derived extracellular vesicles in cancer treatment: opportunities and challenges10.3390/cells9051171 ↗
14. Communication by extracellular vesicles: where we are and where we need to go10.1016/j.cell.2016.01.043 ↗
15. Harnessing the exosome-induced immune response for cancer immunotherapy10.1016/j.semcancer.2014.05.003 ↗
16. Regulation of immune responses by extracellular vesicles10.1038/nri3622 ↗
17. The emerging roles of exosomes in the modulation of immune responses in cancer10.1186/s13073-018-0535-4 ↗
18. Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function10.7150/thno.21234 ↗
19. Mesenchymal stem cell-derived extracellular vesicles: a possible therapeutic strategy for orthopaedic diseases: a narrative review
20. Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis10.7150/thno.22958 ↗
21. Local delivery of USC-derived exosomes harboring ANGPTL3 enhances spinal cord functional recovery after injury by promoting angiogenesis10.1186/s13287-020-02078-8 ↗
22. Extracellular vesicles from human urine-derived stem cells inhibit glucocorticoid-induced osteonecrosis of the femoral head by transporting and releasing pro-angiogenic DMBT1 and anti-apoptotic TIMP110.1016/j.actbio.2020.05.020 ↗
23. Extracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG10.1038/s41413-019-0056-9 ↗
24. Current advances in research and clinical applications of PLGA-based nanotechnology10.1586/erm.09.15 ↗
25. Exosomes from human urine-derived stem cells encapsulated into PLGA nanoparticles for therapy in mice with particulate polyethylene-induced osteolysis
26. The inducible microRNA-21 negatively modulates the inflammatory response in teleost fish via targeting IRAK410.3389/fimmu.2019.01623 ↗
27. The involvement of MicroRNAs in modulation of innate and adaptive immunity in systemic lupus erythematosus and lupus nephritis10.1155/2018/4126106 ↗
28. Extracellular vesicles from human urine-derived stem cells ameliorate particulate polyethylene-induced osteolysis10.2147/IJN.S325646 ↗
29. Differential expression of miRNAs in trichloroethene-mediated inflammatory/autoimmune response and its modulation by sulforaphane: delineating the role of miRNA-21 and miRNA-69010.3389/fimmu.2022.868539 ↗
30. Turning 21: induction of miR-21 as a key switch in the inflammatory response10.3389/fimmu.2015.00019 ↗
31. Nanoparticle delivery of miRNA-21 mimic to cardiac macrophages improves myocardial remodeling after myocardial infarction10.1021/acs.nanolett.8b02578 ↗
32. EVmiRNA: a database of miRNA profiling in extracellular vesicles10.1093/nar/gky985 ↗
33. Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses10.4049/jimmunol.1302167 ↗
34. Human urine-derived stem cell-derived exosomal miR-21-5p promotes neurogenesis to attenuate Rett syndrome via the EPha4/TEK axis10.1038/s41374-021-00574-w ↗
35. Exosomes secreted by urine-derived stem cells improve stress urinary incontinence by promoting repair of pubococcygeus muscle injury in rats10.1186/s13287-019-1182-4 ↗
36. Extracellular vesicles from human urine-derived stem cells ameliorate erectile dysfunction in a diabetic rat model by delivering PPro-angiogenic MicroRNA10.1016/j.esxm.2019.02.001 ↗
37. Extracellular vesicles secreted by human urine-derived stem cells promote ischemia repair in a mouse model of hind-limb ischemia10.1159/000490214 ↗
38. Exosomes secreted by human urine-derived stem cells could prevent kidney complications from type I diabetes in rats10.1186/s13287-016-0287-2 ↗
39. Efficient production and enhanced tumor delivery of engineered extracellular vesicles10.1016/j.biomaterials.2016.07.003 ↗
40. Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF110.1038/ncomms11150 ↗
41. mir-21 overexpressing mesenchymal stem cells accelerate fracture healing in a rat closed femur fracture model10.1155/2015/412327 ↗
42. Adrenaline inhibits osteogenesis via repressing miR-21 expression10.1002/cbin.10685 ↗
43. Extracellular vesicles from human umbilical cord blood ameliorate bone loss in senile osteoporotic mice10.1016/j.metabol.2019.01.009 ↗
44. Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism10.7150/thno.39238 ↗
45. MiR-21 promotes fracture healing by activating the PI3K/Akt signaling pathway
46. MicroRNAs control hepatocyte proliferation during liver regeneration10.1002/hep.23547 ↗
47. Overexpression of miR‑21 promotes neural stem cell proliferation and neural differentiation via the Wnt/β‑catenin signaling pathway in vitro
48. Systemic administration of exosomes released from mesenchymal stromal cells attenuates apoptosis, inflammation, and promotes angiogenesis after spinal cord injury in rats10.1089/neu.2017.5063 ↗
49. miR-21-5p targets SKP2 to reduce osteoclastogenesis in a mouse model of osteoporosis10.1016/j.jbc.2021.100617 ↗