Harnessing the power of hydroxyapatite nanoparticles for gene therapy
Bibliographic record
Abstract
No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.
Source: Not provided · Quality: missing
Research context
OpenAlex topics: RNA Interference and Gene Delivery · Bone Tissue Engineering Materials · Virus-based gene therapy research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. In vivo delivery of miRNAs for cancer therapy: challenges and strategies10.1016/j.addr.2014.05.009 ↗
2. Gene therapy comes of age10.1126/science.aan4672 ↗
3. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus10.1016/j.joca.2016.03.018 ↗
4. Non-viral vectors for gene-based therapy10.1038/nrg3763 ↗
5. Immune responses to viral gene therapy vectors10.1016/j.ymthe.2020.01.001 ↗
6. Non-viral gene therapy: gains and challenges of non-invasive administration methods10.1016/j.jconrel.2015.12.012 ↗
7. Nonviral cancer gene therapy: delivery cascade and vector nanoproperty integration10.1016/j.addr.2017.07.021 ↗
8. Lipid nanoparticle systems for enabling gene therapies10.1016/j.ymthe.2017.03.013 ↗
9. Polymeric delivery of therapeutic nucleic acids10.1021/acs.chemrev.0c00997 ↗
10. Gold nanoparticles for nucleic acid delivery10.1038/mt.2014.30 ↗
11. Mesoporous silica nanoparticles in medicine-recent advances10.1016/j.addr.2012.07.018 ↗
12. Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain10.1016/j.jconrel.2020.01.009 ↗
13. New generation cadmium-free quantum dots for biophotonics and nanomedicine10.1021/acs.chemrev.6b00290 ↗
14. Calcium phosphate nanoparticles-based systems for rnai delivery: applications in bone tissue regeneration10.3390/nano10010146 ↗
15. Hydroxyapatite as a biomaterial–a gift that keeps on giving10.1080/03639045.2020.1776321 ↗
16. A new technique for the assay of infectivity of human adenovirus 5 DNA10.1016/0042-6822(73)90341-3 ↗
17. Hydroxyapatite nanoparticles as a novel gene carrier10.1023/B:NANO.0000034721.06473.23 ↗
18. pDNA loaded calcium phosphate nanoparticles: highly efficient non-viral vector for gene delivery10.1016/j.ijpharm.2004.07.035 ↗
19. Design and in vitro release study of siRNA loaded Layer by Layer nanoparticles with sustained gene silencing effect10.1080/17425247.2018.1518426 ↗
20. Biodegradable calcium phosphate nanoparticles for cancer therapy10.1016/j.cis.2020.102157 ↗
21. The effect of glucose modification of hydroxyapatite nanoparticles on gene delivery10.1002/jbm.a.36523 ↗
22. Cardiomyocyte uptake mechanism of a hydroxyapatite nanoparticle mediated gene delivery system10.3762/bjnano.11.150 ↗
23. Self-fluorescence property of octa-arginine functionalized hydroxyapatite nanoparticles aids in studying their intracellular fate in R1 ESCs10.1016/j.bbrc.2022.08.012 ↗
24. Novel magnetic hydroxyapatite nanoparticles as non-viral vectors for the glial cell line-derived neurotrophic factor gene10.1002/adfm.200901108 ↗
25. Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics10.1038/s41565-021-00858-8 ↗
26. Endocytosis in cancer and cancer therapy10.1038/s41568-023-00574-6 ↗
27. Mitochondria-targeted hydroxyapatite nanoparticles for selective growth inhibition of lung cancer in vitro and in vivo10.1021/acsami.6b06094 ↗
28. Antitumor effect by hydroxyapatite nanospheres: activation of mitochondria-dependent apoptosis and negative regulation of phosphatidylinositol-3-kinase/protein kinase B pathway10.1021/acsnano.8b01996 ↗
29. Adeno-associated virus vector as a platform for gene therapy delivery10.1038/s41573-019-0012-9 ↗
30. Brief update on endocytosis of nanomedicines10.1016/j.addr.2019.08.004 ↗
31. Overcoming nonviral gene delivery barriers: perspective and future10.1021/mp400467x ↗
32. SiRNA-loaded hydroxyapatite nanoparticles for KRAS gene silencing in anti-pancreatic cancer therapy10.3390/pharmaceutics13091428 ↗
33. Synthesis and characterization of a lamellar hydroxyapatite/DNA nanohybrid10.1016/j.matchemphys.2010.12.060 ↗
34. Antitumoural hydroxyapatite nanoparticles-mediated hepatoma-targeted trans-arterial embolization gene therapy: in vitro and in vivo studies10.1111/j.1478-3231.2012.02761.x ↗
35. Nano-hydroxyapatite-derived drug and gene co-delivery system for anti-angiogenesis therapy of breast cancer10.12659/MSM.902538 ↗
36. Design of a biocompatible hydroxyapatite-based nanovehicle for efficient delivery of small interference ribonucleic acid into mouse embryonic stem cells10.1021/acs.molpharmaceut.0c00684 ↗
37. Delivery materials for siRNA therapeutics10.1038/nmat3765 ↗
38. The current state and future directions of RNAi-based therapeutics10.1038/s41573-019-0017-4 ↗
39. Regulation of microRNA biogenesis10.1038/nrm3838 ↗
40. RNAi-based therapeutics and tumor targeted delivery in cancer10.1016/j.addr.2022.114113 ↗
41. siRNA vs. shRNA: similarities and differences10.1016/j.addr.2009.04.004 ↗
42. Decoding cellular mechanism of recombinant adeno-associated virus (rAAV) and engineering host-cell factories toward intensified viral vector manufacturing10.1016/j.biotechadv.2024.108322 ↗
43. Tissue-specific and transcription factor-mediated nuclear entry of DNA10.1016/j.addr.2009.02.008 ↗
44. Nonviral cancer gene therapy: delivery cascade and vector nanoproperty integration10.1016/j.addr.2017.07.021 ↗
45. Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems10.1038/sj.gt.3301635 ↗
46. NLS bioconjugates for targeting therapeutic genes to the nucleus10.1016/S0169-409X(02)00184-9 ↗
47. Noncovalently linked nuclear localization peptides for enhanced calcium phosphate transfection10.1385/MB:33:1:1 ↗
48. Nanostructured calcium phosphates (NanoCaPs) for non-viral gene delivery: influence of the synthesis parameters on transfection efficiency10.1016/j.biomaterials.2006.10.026 ↗
49. Freeze-dried cationic calcium phosphate nanorods as versatile carriers of nucleic acids (DNA, siRNA)10.1039/C1JM13502C ↗
50. Gene delivery using calcium phosphate nanoparticles: optimization of the transfection process and the effects of citrate and poly(l-lysine) as additives10.1016/j.jcis.2016.03.007 ↗
51. Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking10.1002/smll.201201390 ↗
52. Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles10.1016/j.jconrel.2013.09.013 ↗
53. In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles10.1039/C5CS00541H ↗
54. Engineering precision nanoparticles for drug delivery
55. The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction10.2217/nnm.16.5 ↗
56. Control of polymeric nanoparticle size to improve therapeutic delivery10.1016/j.jconrel.2015.10.006 ↗
57. The anti-tumor effect of p53 gene-loaded hydroxyapatite nanoparticles in vitro and in vivo10.1007/s11051-014-2353-y ↗
58. Self-assembled magnetic lamellar hydroxyapatite as an efficient nano-vector for gene delivery10.1016/j.cap.2015.04.032 ↗
59. Controlled template synthesis of lamellar hydroxyapatite nanoplates as a potential carrier for gene delivery10.1016/j.matchemphys.2015.03.011 ↗
60. Substituted Hydroxyapatites for Biomedical Applications: a review10.1016/j.ceramint.2015.03.316 ↗
61. Substituted hydroxyapatite: a recent development10.1080/10667857.2019.1664096 ↗
62. Nanostructured silicate substituted calcium phosphate (NanoSiCaPs) nanoparticles — Efficient calcium phosphate based non-viral gene delivery systems10.1016/j.msec.2016.06.076 ↗
63. Controlled release of DNA from zinc and magnesium ion-doped hydroxyapatites10.1007/s11164-018-3626-3 ↗
64. Arginine functionalized hydroxyapatite nanoparticles and its bioactivity for gene delivery10.1016/S1003-6326(15)63629-9 ↗
65. Surface cationic functionalized nano-hydroxyapatite – Preparation, characterization, effect of coverage on properties and related applications10.1016/j.eurpolymj.2020.109759 ↗
66. Controlling the release profile through phase control of calcium phosphate-alginate core-shell nanoparticles in gene delivery10.1007/s13233-019-7106-4 ↗
67. Surface-modified hydroxyapatite nanoparticle for microRNA delivery to regulate gene expression in human mandibular osteoblast cells10.1007/s11051-020-05121-0 ↗
68. Preparation and characterization of chitosan-coated hydroxyapatite nanoparticles as a promising non-viral vector for gene delivery10.1002/app.34140 ↗
69. Development of novel gene carrier using modified nano hydroxyapatite derived from equine bone for osteogenic differentiation of dental pulp stem cells
70. Hydroxyapatite nanoparticles modified by branched polyethylenimine are effective non-viral vectors for siRNA transfection of hepatoma cells in vitro10.3892/ijo.2015.2918 ↗
71. One-step synthesis of nanosized and stable amino-functionalized calcium phosphate particles for DNA transfection10.1021/cm401886u ↗
72. Adsorption of myoglobin onto various synthetic hydroxyapatite particles10.1039/a909396f ↗
73. Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents10.1002/jbm.b.31746 ↗
74. Synthesis methods for nanosized hydroxyapatite with diverse structures10.1016/j.actbio.2013.04.012 ↗
75. Inhibition of human glioma U251 cells growth in vitro and in vivo by hydroxyapatite nanoparticle-assisted delivery of short hairpin RNAs against SATB110.1007/s11033-013-2942-3 ↗
76. The cooperative effect of p53 and Rb in local nanotherapy in a rabbit VX2 model of hepatocellular carcinoma
77. Inhibition of prostate cancer RM1 cell growth in vitro by hydroxyapatite nanoparticle-delivered short hairpin RNAs against Stat310.3892/mmr.2017.6583 ↗
78. DNA-templated strontium-doped calcium phosphate nanoparticles for gene delivery in bone cells10.1021/acsbiomaterials.8b01587 ↗
79. Mineralized vectors for gene therapy10.1016/j.actbio.2022.05.036 ↗
80. Functionalized porous hydroxyapatite scaffolds for tissue engineering applications: a focused review10.1021/acsbiomaterials.1c00438 ↗
81. Amine functionalised hydroxyapatite nanoparticles for anti-angiogenesis gene therapy of breast cancer10.1049/mnl.2016.0078 ↗
82. Transfection system of amino-functionalized calcium phosphate nanoparticles: in vitro efficacy, biodegradability, and immunogenicity study10.1021/am507193a ↗
83. The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells
84. Enhancing endosomal escape for nanoparticle mediated siRNA delivery10.1039/c4nr00018h ↗
85. Mechanism of polyplex- and lipoplex-mediated delivery of nucleic acids: real-time visualization of transient membrane destabilization without endosomal lysis10.1021/nn3049494 ↗
86. Endosomal escape pathways for delivery of biologicals10.1016/j.jconrel.2010.11.004 ↗
87. The endosomal escape of nanoparticles: toward more efficient cellular delivery10.1021/acs.bioconjchem.8b00732 ↗
88. Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies10.1021/acs.chemrev.5b00589 ↗
89. Use of magnetic fields and nanoparticles to trigger drug release and improve tumor targeting10.1002/wnan.1571 ↗
90. Iron oxide nanoparticles: diagnostic, therapeutic and theranostic applications10.1016/j.addr.2019.01.005 ↗
91. Magnetically deliverable calcium phosphate nanoparticles for localized gene expression10.1039/C4RA13413C ↗
92. Marycz · Int. J. Nanomedicine · 2021 · 16 · 342910.2147/IJN.S303412 ↗
93. Different hydroxyapatite magnetic nanoparticles for medical imaging: its effects on hemostatic, hemolytic activity and cellular cytotoxicity10.1016/j.colsurfb.2016.06.042 ↗
94. Magnetic field and nano-scaffolds with stem cells to enhance bone regeneration10.1016/j.biomaterials.2018.08.040 ↗
95. Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cell-mediated bone formation10.1002/adma.201103828 ↗
96. Mesenchymal stem cell fate following non-viral gene transfection strongly depends on the choice of delivery vector10.1016/j.actbio.2017.03.044 ↗
97. Calcium phosphate nanoneedle based gene delivery system for cancer genetic immunotherapy10.1016/j.biomaterials.2020.120072 ↗
98. Combinatorial gene therapy accelerates bone regeneration: non-viral dual delivery of VEGF and BMP2 in a collagen-nanohydroxyapatite scaffold10.1002/adhm.201400397 ↗
99. Rapid bone repair with the recruitment of CD206+M2-like macrophages using non-viral scaffold-mediated miR-133a inhibition of host cells10.1016/j.actbio.2020.03.042 ↗
100. Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing: dual MicroRNA Delivery Accelerates Bone Healing10.1016/j.actbio.2023.09.049 ↗