journal article·2024-04

Improving mitochondrial function for alleviating memory decline of aging mice via dual-delivering lycopene nanoparticles

Xiaoyu Xia, Han Li, Xianbing Xu, Zhenyu Wang, Guanghua Zhao, Ming Du

Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Antioxidant Activity and Oxidative Stress · Mitochondrial Function and Pathology · Medicinal Plants and Neuroprotection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (48)

Show source-provided references
1. Alzheimer's disease10.1016/S0140-6736(20)32205-4 ↗
2. MPTP and Parkinson's disease10.1016/0166-2236(85)90031-1 ↗
3. Brain-neuron targeted nanoparticles for peptide synergy therapy at dual-target of Alzheimer's disease10.1016/j.jconrel.2023.01.074 ↗
4. Add-on drug approved for "Off" episodes of parkinson disease
5. Accelerating research for Parkinson's disease10.1016/S1474-4422(18)30081-4 ↗
6. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing10.1038/s41573-020-0072-x ↗
7. Targeted mitochondrial delivery: a therapeutic new era for disease treatment10.1016/j.jconrel.2022.01.025 ↗
8. Disturbed mitochondrial dynamics and neurodegenerative disorders10.1038/nrneurol.2014.228 ↗
9. Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity10.1038/s41467-017-00043-3 ↗
10. Lycopene in human health10.1016/j.lwt.2020.109323 ↗
11. A review for the pharmacological effect of lycopene in central nervous system disorders10.1016/j.biopha.2018.12.151 ↗
12. Lycopene protects against trimethyltin-induced neurotoxicity in primary cultured rat hippocampal neurons by inhibiting the mitochondrial apoptotic pathway10.1016/j.neuint.2011.10.005 ↗
13. Protective effects of lycopene against methylmercury-induced neurotoxicity in cultured rat cerebellar granule neurons10.1016/j.brainres.2013.10.005 ↗
14. Encapsulation of lycopene into electrospun nanofibers from whey protein isolate-Tricholoma lobayense polysaccharide complex stabilized emulsions: structural characterization, storage stability, in vitro release, and cellular evaluation10.1016/j.ijbiomac.2023.123993 ↗
15. Acetylated cashew gum and fucan for incorporation of lycopene rich extract from red guava (Psidium guajava L.) in nanostructured systems: antioxidant and antitumor capacity10.1016/j.ijbiomac.2021.09.116 ↗
16. H-ferritin-nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection10.1073/pnas.1407808111 ↗
17. Targeted delivery of PARP inhibitors to neuronal mitochondria via biomimetic engineered nanosystems in a mouse model of traumatic brain injury10.1016/j.actbio.2021.12.023 ↗
18. Custom-Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia10.1002/anie.201802309 ↗
19. Endo/lysosome-escapable delivery depot for improving BBB transcytosis and neuron targeted therapy of Alzheimer's disease10.1002/adfm.201909999 ↗
20. Regulation of cell uptake and cytotoxicity by nanoparticle core under the controlled shape, size, and surface chemistries10.1021/acsnano.9b04407 ↗
21. Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases10.1038/s41467-020-16544-7 ↗
22. Ferritin cage for encapsulation and delivery of bioactive nutrients: from structure, property to applications10.1080/10408398.2016.1149690 ↗
23. Fenozyme protects the integrity of the blood-brain barrier against experimental cerebral malaria10.1021/acs.nanolett.9b03774 ↗
24. PM1-loaded recombinant human H-ferritin nanocages: a novel pH-responsive sensing platform for the identification of cancer cells10.1016/j.ijbiomac.2021.12.068 ↗
25. Encapsulation of curcumin in recombinant human H-chain ferritin increases its water-solubility and stability10.1016/j.foodres.2014.05.054 ↗
26. LYC loaded ferritin nanoparticles for intracerebral delivery and the attenuation of neurodegeneration in D-gal-induced mice
27. ROS production in homogenate from the body wall of sea cucumber Stichopus japonicus under UVA irradiation: ESR spin-trapping study10.1016/j.foodchem.2015.07.030 ↗
28. Biomimetic design of mitochondria-targeted hybrid nanozymes as superoxide scavengers10.1002/adma.202006570 ↗
29. Self-protecting biomimetic nanozyme for selective and synergistic clearance of peripheral amyloid-beta in an Alzheimer's disease model10.1021/jacs.0c08395 ↗
30. Chiral molecule-mediated porous Cu (x)O nanoparticle clusters with antioxidation activity for ameliorating Parkinson's disease10.1021/jacs.8b11856 ↗
31. Biomimetic dendrimer-peptide conjugates for early multi-target therapy of Alzheimer's disease by inflammatory microenvironment modulation10.1002/adma.202100746 ↗
32. Targeting antioxidants to mitochondria by conjugation to lipophilic cations10.1146/annurev.pharmtox.47.120505.105110 ↗
33. Facilitating pro-survival mitophagy for alleviating Parkinson's disease via sequence-targeted lycopene nanodots10.1021/acsnano.3c04308 ↗
34. Ferritin nanocarrier traverses the blood brain barrier and kills glioma10.1021/acsnano.7b06969 ↗
35. Mitochondrial fission in apoptosis10.1038/nrm1697 ↗
36. Postsynaptic protein phosphorylation and LTP10.1016/S0166-2236(99)01490-3 ↗
37. Sea cucumber peptides attenuated the scopolamine-induced memory impairment in mice and rats and the underlying mechanism10.1021/acs.jafc.1c06475 ↗
38. The role of calmodulin as a signal integrator for synaptic plasticity10.1038/nrn1647 ↗
39. Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice10.1016/j.bbr.2010.08.033 ↗
40. Maltol (3-hydroxy-2-methyl-4-pyrone) slows d-galactose-induced brain aging process by damping the Nrf2/HO-1-mediated oxidative stress in mice10.1021/acs.jafc.9b04614 ↗
41. How neuroinflammation contributes to neurodegeneration10.1126/science.aag2590 ↗
42. MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia10.1016/j.biomaterials.2016.03.025 ↗
43. iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice
44. Loading neural stem cells on hydrogel scaffold improves cell retention rate and promotes functional recovery in traumatic brain injury
45. The use of nano-quercetin to arrest mitochondrial damage and MMP-9 upregulation during prevention of gastric inflammation induced by ethanol in rat10.1016/j.biomaterials.2011.12.037 ↗
46. Intranasal exposure to ZnO nanoparticles induces alterations in cholinergic neurotransmission in rat brain10.1016/j.nantod.2020.100977 ↗
47. Basic roles of key molecules connected with NMDAR signaling pathway on regulating learning and memory and synaptic plasticity
48. Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer's disease10.1038/s41593-018-0080-x ↗