Biomimetic lipid membranes: An overview on their properties and applications
Source abstract
Abstract
Cell membranes are complex biological bilayer-like structures made up of various phospholipids and proteins as main components. Biomimetic lipid membranes are model systems characterized by physical and chemical properties like those of the cell bilayer. This review describes the advancements made in the development of phospholipid bilayers focusing on the “black lipid membranes”, the “supported lipid membranes” and the “tethered lipid membranes”. The aim is to provide an overview of their physico-chemical properties and their applications in various fields. In detail, their use as detection systems for various molecules (biosensors) and as biocapacitors with the ability to generate clean energy are discussed.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanopore and Nanochannel Transport Studies · Lipid Membrane Structure and Behavior · Fuel Cells and Related Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. The fluid mosaic model of the structure of cell membranes10.1126/science.175.4023.720 ↗
2. An overview of neutron scattering and molecular dynamics simulation studies of phospholipid bilayers in room-temperature ionic liquid/water solutions10.1016/j.physb.2018.02.043 ↗
3. Membrane protein–lipid interactions probed using mass spectrometry10.1146/annurev-biochem-013118-111508 ↗
4. Membrane lipid composition: effect on membrane and organelle structure, function and compartmentalization and therapeutic avenues10.3390/ijms20092167 ↗
5. Mimicking the mammalian plasma membrane: an overview of lipid membrane models for biophysical studies
6. Understanding the diversity of membrane lipid composition10.1038/nrm.2017.138 ↗
7. Shedding light on the structural properties of lipid bilayers using molecular dynamics simulation: a review study
8. The pore-forming action of polyenes: from model membranes to living organisms10.1016/j.bbamem.2018.11.006 ↗
9. The fundamental interaction of cholesterol with lipid membranes: the umbrella model
10. Cell–cell communication: old mystery and new opportunity10.1007/s10565-019-09470-y ↗
11. Strategies for monitoring cell–cell interactions10.1038/s41589-021-00790-x ↗
12. Methods for the formation of single bimolecular lipid membranes in aqueous solution [1]10.1021/j100796a529 ↗
13. Rapid fabrication of teflon apertures by controlled high voltage pulses for formation of free-standing planar lipid bilayer membrane10.1007/s10544-021-00553-4 ↗
14. Electrode-supported and free-standing bilayer lipid membranes: formation and uses in molecular electrochemistry10.1002/elsa.202100170 ↗
15. Supported lipid bilayer coatings: fabrication, bioconjugation, and diagnostic applications
16. Supported lipid bilayer formation: beyond vesicle fusion10.1021/acs.langmuir.9b03706 ↗
17. AFM for structure and dynamics of biomembranes10.1016/j.bbamem.2008.08.021 ↗
18. Supported phospholipid bilayers10.1016/S0006-3495(85)83882-0 ↗
19. Structure, formation, and biological interactions of supported lipid bilayers (SLB) incorporating lipopolysaccharide10.3390/coatings10100981 ↗
20. Transport and organization of cholesterol in a planar solid-supported lipid bilayer depend on the phospholipid flip-flop rate10.1021/acs.langmuir.6b02560 ↗
21. Supported lipid bilayers for the generation of dynamic cell–material interfaces10.1002/adhm.201500398 ↗
22. Melting-temperature-dependent interactions of ergosterol with unsaturated and saturated lipids in model membranes10.1021/acs.langmuir.9b01538 ↗
23. Effect of cholesterol on the fluidity of supported lipid bilayers10.1016/j.colsurfb.2020.111353 ↗
24. Diffusion in supported lipid bilayers: influence of substrate and preparation technique on the internal dynamics10.1140/epje/i2008-10407-3 ↗
25. Self-assembled fluid phase floating membranes with tunable water interlayers10.1021/acs.langmuir.9b02350 ↗
26. Tethered lipid bilayer membranes: formation and ionic reservoir characterization10.1021/la9711239 ↗
27. Functional activity of peptide ion channels in tethered bilayer lipid membranes: review10.1002/elsa.202100180 ↗
28. Tethered membrane architectures—design and applications10.3389/fmats.2018.00055 ↗
29. Biological applications of tethered bilayer lipid membranes10.1016/j.biochi.2018.11.011 ↗
30. The use of giant unilamellar vesicles to study functional properties of pore-forming toxins
31. Recent developments in the field of bending rigidity measurements on membranes10.1016/j.cis.2014.03.003 ↗
32. Clathrin senses membrane curvature10.1016/j.bpj.2020.12.035 ↗
33. The membrane transporter lactose permease increases lipid bilayer bending rigidity
34. Facile generation of biomimetic-supported lipid bilayers on conducting polymer surfaces for membrane biosensing10.1021/acsami.9b10303 ↗
35. Hybrid bilayer membranes as platforms for biomimicry and catalysis10.1038/s41570-022-00433-2 ↗
36. Biomedical applications: liposomes and supported lipid bilayers for diagnostics, theranostics, imaging, vaccine formulation, and tissue engineering
37. Mechanistic evaluation of antimicrobial lipid interactions with tethered lipid bilayers by electrochemical impedance spectroscopy10.3390/s22103712 ↗
38. Surface modification of iron oxide-based magnetic nanoparticles for cerebral theranostics: application and prospection10.3390/nano10081441 ↗
39. Biosensors based on bio-functionalized semiconducting metal oxides
40. Current signal amplification strategies in aptamer-based electrochemical biosensor: a review10.1016/j.cclet.2020.12.054 ↗
41. Manipulating endoplasmic reticulum-plasma membrane tethering in plants through fluorescent protein complementation10.3389/fpls.2019.00635 ↗
42. Detection of right-to-left shunts with an arterial potentiometric electrode10.1161/01.CIR.22.5.949 ↗
43. Mini-review: potential of diatom-derived silica for biomedical applications10.3390/app11104533 ↗
44. Recent lipid membrane-based biosensing platforms10.3390/app9091745 ↗
45. Biosensors applications in medical field: a brief review
46. Bacterial membrane mimetics: from biosensing to disease prevention and treatment10.3390/bios13020189 ↗
47. Electrochemical response of redox amino acid encoded fluorescence protein for hydroxychloroquine sensing10.1007/s12010-022-04142-w ↗
48. Recent advances in FRET-based biosensors for biomedical applications10.1016/j.ab.2021.114323 ↗
49. Reconstitution of cell membrane structure in vitro and its transformation into an excitable system10.1038/194979a0 ↗
50. Voltage-induced capacitance relaxation of lipid bilayer membranes Effects of membrane composition10.1016/0005-2736(76)90043-2 ↗
51. Mechanically enhancing planar lipid bilayers with a minimal actin cortex10.1021/acs.langmuir.8b01847 ↗
52. Electrochemical impedance spectroscopy for black lipid membranes fused with channel protein supported on solid-state nanopore10.1007/s00249-016-1156-8 ↗
53. Multimodal Investigation into the Interaction of quinacrine with microcavity-supported lipid bilayers10.1021/acs.langmuir.2c00524 ↗
54. Formation and characterization of air-stable lipid bilayer membranes incorporated with phthalocyanine molecules10.1021/acs.jpcb.9b05135 ↗
55. Planar bilayer membranes made from phospholipid monolayers form by a thinning process10.1016/S0006-3495(88)83110-2 ↗
56. Characterizing the structure and interactions of model lipid membranes using electrophysiology10.3390/membranes11050319 ↗
57. A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment10.1038/ncomms5916 ↗
58. Investigating the structural properties of hydrophobic solvent-rich lipid bilayers10.1039/D0SM02270E ↗
59. Determining membrane capacitance by dynamic control of droplet interface bilayer area10.1021/la203081v ↗
60. In vitro application of langmuir monolayer model: the interfacial behavior of myelin basic protein with a plasma membrane model10.1007/s00232-022-00214-4 ↗
61. Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties10.1073/pnas.69.12.3561 ↗
62. Thin film composite membrane compaction in high-pressure reverse osmosis10.1016/j.memsci.2020.118268 ↗
63. Electromechanical characterization of biomimetic membranes using electrodeformation of vesicles10.1002/elps.202100091 ↗
64. A chip-based array for high-resolution fluorescence characterization of free-standing horizontal lipid membranes under voltage clamp10.1039/D2LC00357K ↗
65. J.A. Cohen, B. Gabriel, J. Teissié, M. Winterhalter, Transmembrane voltage sensor, in: 2003: pp. 847–886. 10.1016/S0927-5193(03)80055-4.10.1016/S0927-5193(03)80055-4 ↗
66. Black lipid membranes: visualizing the structure, dynamics, and substrate dependence of membranes10.1021/jp048098h ↗
67. Electrochemical triggering of lipid bilayer lift-off oscillation at the electrode interface10.1098/rsif.2018.0626 ↗
68. Transient domains of ordered water induced by divalent ions lead to lipid membrane curvature fluctuations10.1038/s42004-020-0263-8 ↗
69. Model membrane systems used to study plasma membrane lipid asymmetry10.3390/sym13081356 ↗
70. Molecular mechanisms of polymyxin β-membrane interactions: direct correlation between surface charge density and self-promoted transport10.1007/s002329900350 ↗
71. Measuring lipid asymmetry in planar supported bilayers by fluorescence interference contrast microscopy10.1021/la047654w ↗
72. Tuning lipid mixtures to induce or suppress domain formation across leaflets of unsupported asymmetric bilayers10.1073/pnas.0702970105 ↗
73. Engineering asymmetric vesicles10.1073/pnas.1931005100 ↗
74. Asymmetric bilayers by hemifusion: method and leaflet behaviors10.1016/j.bpj.2019.07.054 ↗
75. Gramicidin increases lipid flip-flop in symmetric and asymmetric lipid vesicles10.1016/j.bpj.2019.01.016 ↗
76. Clair · 2017 · 1
77. A comprehensive comparison of transmembrane domains reveals organelle-specific properties10.1016/j.cell.2010.05.037 ↗
78. H.T. Tien, a L. Ottova, Membrane Biophysics as viewed from experimental bilayer lipid membranes, 2000.
79. Polynucleotide transport through lipid membrane in the presence of starburst cyclodextrin-based poly (Ethylene glycol) s10.1140/epje/i2018-11743-3 ↗
80. Lipid membrane models for biomembrane properties’ investigation
81. Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c10.1074/jbc.275.16.12321 ↗
82. Arrayed lipid bilayer chambers allow single-molecule analysis of membrane transporter activity10.1038/ncomms5519 ↗
83. Porin from marine bacterium marinomonas primoryensis KMM 3633T: isolation, physico-chemical properties, and functional activity10.3390/molecules25143131 ↗
84. R-type fonticins produced by pragia fontium form large pores with high conductance10.1128/jb.00315-22 ↗
85. Formation and stability of a suspended biomimetic lipid bilayer on silicon submicrometer-sized pores10.1016/j.jcis.2006.11.050 ↗
86. Bilayer lipid membranes supported on Teflon filters: a functional environment for ion channels10.1016/j.bios.2010.12.013 ↗
87. Black lipid membranes: challenges in simultaneous quantitative characterization by electrophysiology and fluorescence microscopy10.1021/acs.langmuir.9b00673 ↗
88. Black lipid membranes10.1016/S1359-0294(00)00063-7 ↗
89. Droplet interface bilayers10.1039/b808893d ↗
90. Direct in situ measurement of specific capacitance, monolayer tension, and bilayer tension in a droplet interface bilayer10.1039/C5SM01005E ↗
91. Temperature-dependent structural changes in planar bilayer membranes: solvent “freeze-out”10.1016/0005-2736(74)90289-2 ↗
92. Alkylated glass partition allows formation of solvent-free lipid bilayer by Montal-Mueller technique10.1016/j.bioelechem.2008.02.002 ↗
93. Toward realistic large-area cell membrane mimics: excluding oil, controlling composition, and including ion channels10.1021/acs.langmuir.8b00837 ↗
94. Highly reproducible method of planar lipid bilayer reconstitution in polymethyl methacrylate microfluidic chip10.1021/la052534p ↗
95. Lipid bilayer formation by contacting monolayers in a microfluidic device for membrane protein analysis10.1021/ac0613479 ↗
96. Supported lipid bilayers as models for studying membrane domains
97. Interaction of poly(ethylene glycol)-conjugated phospholipids with supported lipid membranes and their influence on protein adsorption10.1080/14686996.2016.1240006 ↗
98. Advances in nanopatterned and nanostructured supported lipid membranes and their applications10.1080/02648725.2010.10648150 ↗
99. Solid supported lipid bilayers: from biophysical studies to sensor design10.1016/j.surfrep.2006.06.001 ↗
100. Solid-supported lipid bilayers – A versatile tool for the structural and functional characterization of membrane proteins10.1016/j.ymeth.2020.09.005 ↗