Edible hydrogels with shrinkage tolerance in acids and stomach-friendly mechanical moduli
Source abstract
Abstract
Healthcare devices for the human body have seen continuous evolution, from external wear to wearables, and now to entirely concealed placements. The gastrointestinal (GI) tract offers considerable surface area for medical device introduction. In particular, hydrogels have been explored for disease treatment, specifically for long-term gastric retention to aid in bodyweight control. The current method of oral administration of hydrogels is challenged by two problems, namely, non-edibility and low shrinkage tolerance in acids, which prevents their practical application. In this paper, a new type of edible natural polymer-based hydrogel possessing a desired balance of swelling behavior in both neutral and acidic environments is introduced. Results based on animal experiments have shown that these edible hydrogels are a safe and efficient method for bodyweight control. The new edible material offers advantages for healthcare applications in the GI tract.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Hydrogels: synthesis, properties, applications · Electrospun Nanofibers in Biomedical Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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