journal article·2022-08

Intestinal delivery of ROS-scavenging carbonized polymer dots for full-course treatment of acute and chronic radiation enteritis

Jiaxin Zhang, Mingxi Yang, Xiaoduo Tang, Shuang Li, Junhu Zhang, Laijin Lu, Quan Wang, Bai Yang

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OpenAlex topics: Carbon and Quantum Dots Applications · Effects of Radiation Exposure · Oral health in cancer treatment

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References (55)

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1. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Chronic Radiation Proctitis10.1097/DCR.0000000000001209 ↗
2. Radiotherapy toxicity10.1038/s41572-019-0064-5 ↗
3. Radiation enteropathy–pathogenesis, treatment and prevention10.1038/nrgastro.2014.46 ↗
4. Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome10.1038/ncomms4492 ↗
5. Highly Catalytic Niobium Carbide (MXene) Promotes Hematopoietic Recovery after Radiation by Free Radical Scavenging10.1021/acsnano.8b09327 ↗
6. New pathways for alimentary mucositis10.1155/2008/907892 ↗
7. Mechanisms of fibrogenesis10.3181/0707-MR-190 ↗
8. The efficacy and safety of amifostine for the acute radiation syndrome10.1080/14740338.2019.1666104 ↗
9. Highly bioactive zeolitic imidazolate framework-8-capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke10.1126/sciadv.aay9751 ↗
10. Oral delivery of micro/nanoparticulate systems based on natural polysaccharides for intestinal diseases therapy: Challenges, advances and future perspectives10.1016/j.jconrel.2021.04.026 ↗
11. ROS-Scavenging Therapeutic Hydrogels for Modulation of the Inflammatory Response
12. Nucleosome-inspired nanocarrier obtains encapsulation efficiency enhancement and side effects reduction in chemotherapy by using fullerenol assembled with doxorubicin10.1016/j.biomaterials.2018.03.015 ↗
13. Carbon nanotubes: promising agents against free radicals10.1039/b9nr00364a ↗
14. Clinically Approved Carbon Nanoparticles with Oral Administration for Intestinal Radioprotection via Protecting the Small Intestinal Crypt Stem Cells and Maintaining the Balance of Intestinal Flora
15. Graphdiyne nanoradioprotector with efficient free radical scavenging ability for mitigating radiation-induced gastrointestinal tract damage10.1016/j.biomaterials.2020.119940 ↗
16. Evolution and Synthesis of Carbon Dots: From Carbon Dots to Carbonized Polymer Dots
17. Deep Red Emissive Carbonized Polymer Dots with Unprecedented Narrow Full Width at Half Maximum10.1002/adma.202007162 ↗
18. Self-Targeting Fluorescent Carbon Dots for Diagnosis of Brain Cancer Cells10.1021/acsnano.5b05575 ↗
19. Carbon Dots Induce Epithelial-Mesenchymal Transition for Promoting Cutaneous Wound Healing via Activation of TGF-β/p38/Snail Pathway
20. Super-Cationic Carbon Quantum Dots Synthesized from Spermidine as an Eye Drop Formulation for Topical Treatment of Bacterial Keratitis10.1021/acsnano.7b01023 ↗
21. Selenium-Doped Carbon Quantum Dots Act as Broad-Spectrum Antioxidants for Acute Kidney Injury Management
22. Carbon Dots Derived from Citric Acid and Glutathione as a Highly Efficient Intracellular Reactive Oxygen Species Scavenger for Alleviating the Lipopolysaccharide-Induced Inflammation in Macrophages10.1021/acsami.0c11735 ↗
23. Chitosan derived nitrogen-doped carbon dots suppress osteoclastic osteolysis via downregulating ROS10.1039/D0NR02848G ↗
24. Salvia Miltiorrhiza-Derived Carbon Dots as Scavengers of Reactive Oxygen Species for Reducing Oxidative Damage of Plants10.1021/acsanm.0c02419 ↗
25. Inhibition of oxidative stress in vivo through enzyme-like activity of carbon dots
26. PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF210.1126/scitranslmed.3008523 ↗
27. Eosinophil depletion suppresses radiation-induced small intestinal fibrosis10.1126/scitranslmed.aan0333 ↗
28. Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis10.1046/j.1365-2249.2000.01183.x ↗
29. Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis10.1152/japplphysiol.00793.2014 ↗
30. Trimmomatic: a flexible trimmer for Illumina sequence data10.1093/bioinformatics/btu170 ↗
31. FLASH assembly of TALENs for high-throughput genome editing10.1038/nbt.2170 ↗
32. QIIME allows analysis of high-throughput community sequencing data10.1038/nmeth.f.303 ↗
33. VSEARCH: a versatile open source tool for metagenomics10.7717/peerj.2584 ↗
34. HISAT: a fast spliced aligner with low memory requirements10.1038/nmeth.3317 ↗
35. Facile synthesis of Mg2+ -doped Carbon dots as novel biomaterial inducing cell osteoblastic differentiation10.1002/ppsc.201800315 ↗
36. Carbon-based dots co-doped with nitrogen and sulfur for high quantum yield and excitation-independent emission10.1002/anie.201301114 ↗
37. Near-infrared emissive carbon dots for two-photon fluorescence bioimaging10.1039/C6NR05878G ↗
38. Selenium-Doped Carbon Quantum Dots for Free-Radical Scavenging10.1002/anie.201705989 ↗
39. Engineering Nano- and Microparticles as Oral Delivery Vehicles to Promote Intestinal Lymphatic Drug Transport10.1002/adma.202104139 ↗
40. Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage10.1016/S0304-4165(02)00339-2 ↗
41. High-throughput preparation of radioprotective polymers via Hantzsch’s reaction for in vivo X-ray damage determination10.1038/s41467-020-20027-0 ↗
42. Modifying radiation damage10.2174/1389450111009011352 ↗
43. Initial events in the cellular effects of ionizing radiations: clustered damage in DNA10.1080/09553009414550021 ↗
44. The comet assay for DNA damage and repair: principles, applications, and limitations10.1385/MB:26:3:249 ↗
45. Role of endogenous thiols in protection10.1016/0273-1177(92)90109-B ↗
46. Interaction of glutathione and other low-molecular-weight thiols with DNA: evidence for counterion condensation and coion depletion near DNA10.2307/3577139 ↗
47. Combination treatment of podophyllotoxin and rutin promotes mouse Lgr5 intestinal stem cells survival against lethal radiation injury through Wnt signaling10.1007/s10495-019-01519-x ↗
48. Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice10.1172/JCI59920 ↗
49. NF-κB signaling in inflammation
50. How nucleotide excision repair protects against cancer10.1038/35094000 ↗
51. The hedgehog and Wnt/β-catenin system machinery mediate myofibroblast differentiation of LR-MSCs in pulmonary fibrogenesis10.1038/s41419-018-0692-9 ↗
52. Intestinal Fibrosis and Gut Microbiota: Clues From Other Organs10.3389/fmicb.2021.694967 ↗
53. Lycium barbarum mitigates radiation injury via regulation of the immune function, gut microbiota, and related metabolites10.1016/j.biopha.2021.111654 ↗
54. Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
55. High-throughput 16S rRNA gene sequencing reveals alterations of mouse intestinal microbiota after radiotherapy10.1016/j.anaerobe.2015.01.004 ↗