journal article·2023-12Open access

Photothermal nanomaterials for theranostics of atherosclerosis and thrombosis

Karla X. Vazquez-Prada, Shehzahdi S. Moonshi, Zhi Ping Xu, Hang Thu Ta

Abstract

Nonradiative therapies focusing on converting energy from light into heat (photothermal therapy, PTT) have been widely studied for the treatment of cancers. In the last years, interests in the potential therapeutic efficiency of PTT in cardiovascular diseases have grown quickly. Nonetheless, research in this field is still limited and requires further attention. One of the advantages of nanocarriers used as photothermal agents is the possibility to integrate multimodal imaging and therapeutic functions as a solution to address the current limitations in the clinic. In this review, we first explain the mechanism of nanoparticle-mediated photothermal therapy and summarize the advances in the development of inorganic, organic, and hybrid nano photothermal transduction agents (PTAs). Then we discuss the toxicity, challenges and limitations encountered in the development of phototherapy for cardiovascular diseases. The review concludes with highlighting possible solutions for improving PTT in this specific field.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photoacoustic and Ultrasonic Imaging · Gold and Silver Nanoparticles Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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