Adsorption of Cd2+ ions on an Egyptian montmorillonite and toxicological effects in rats
Source abstract
Abstract
Abstract Cadmium (Cd 2+ ion) is an ubiquitous environmental pollutant that has been associated with many toxicological disorders in both humans and animal models. The aims of the current study were to study the physiochemical properties of Egyptian montmorillonite (EM), to evaluate its ability to adsorb Cd 2+ ions from aqueous solutions in vitro and to evaluate the protective effects of EM against Cd 2+ ions toxicity in vivo . In the in vitro study, three concentrations of Cd 2+ ions (10, 20 and 50 ppm) and three concentrations of EM (0.5, 1 and 2 g/100 ml aqueous solution) were tested. The in vivo study revealed that Cd 2+ ions induced toxicological and histological changes typical to those reported in the literature. EM was found to counteract these hazards effects. EM is a promising candidate for the removal of Cd 2+ ions from aqueous solution and reducing their toxicity.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Heavy Metal Exposure and Toxicity · Aluminum toxicity and tolerance in plants and animals · Therapeutic Uses of Natural Elements
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (69)
Show source-provided references
1. The protective effect of hydrated sodium calcium aluminosilicate against haematological, biochemical and pathological changes induced by zearalenone in mice10.1016/j.toxicon.2006.01.016 ↗
2. Preventive role of phyllosilicate clay on the immunological and biochemical toxicity of zearalenone in balb/c mice10.1016/j.intimp.2006.03.012 ↗
3. Inactivation of cadmium induced immunotoxicological alterations in rats by Tunisian montmorillonite clay10.1016/j.intimp.2007.01.013 ↗
4. Adsorption of sterigmatocystin by montmorillonite and inhibition of its genotoxicity in the Nile tilapia fish (Oreachromis nilaticus)10.1016/j.mrgentox.2004.12.009 ↗
5. Potential protective effect of HSCAS and bentonite against dietary aflatoxicosis in rat: with special reference to chromosomal aberrations10.1002/(SICI)1522-7189(199809/10)6:5<211::AID-NT31>3.0.CO;2-8 ↗
6. Effect of aluminosilicates and bentonite on aflatoxin-induced developmental toxicity in the rats10.1002/(SICI)1099-1263(199905/06)19:3<199::AID-JAT558>3.0.CO;2-D ↗
7. Physiological and toxicological responses in rats fed aflatoxin-contaminated diet with or without sorbent materials10.1016/S0377-8401(01)00342-X ↗
8. Protection against cadmium-induced toxicity in the rats: potential for hidden risks
9. Reductions in the toxicity of cadmium to microorganisms by clay minerals10.1128/AEM.33.3.696-705.1977 ↗
10. Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2–MMSH6 complex10.1093/nar/gki291 ↗
11. Serum creatinine determination without protein precipitation
12. Cadmium concentrations in the testes, sperm, and spermatids of mice subjected to long-term cadmium chloride exposure10.1002/(SICI)1097-0320(19990101)35:1<30::AID-CYTO5>3.0.CO;2-M ↗
13. Cadmium, gene regulation, and cellular signalling in mammalian cells10.1006/taap.1997.8125 ↗
14. Comparison of natural adsorbents for removal metal from acidic effluent10.1080/09593330309385552 ↗
15. Development of an Algerian material montmorillonite clay—intercalation with selective long chain alkylammonium cations (Octadecytrimethylammonium, Cetylpyridium and Tetrabutylammonium) and with tellerium complexes development of an Algerian material montmorillonite10.1016/j.desal.2007.01.204 ↗
16. Renal tubular dysfunction in male inhabitants of a cadmium-polluted area in Toyama, Japan – an eleven-year follow-up study10.2188/jea.11.180 ↗
17. Cadmium-induced oxidative stress and DNA damage in kidney of pregnant female rats10.1016/j.crvi.2008.03.009 ↗
18. Potential contribution of dietary sources to urinary cadmium and b2-microglobulin excretion of occupationally exposed workers10.1097/00043764-199111000-00016 ↗
19. Hydrated sodium calcium aluminosilicate: effects on zinc, manganese, vitamin A, and riboflavin utilization10.3382/ps.0691364 ↗
20. Removal of cadmium, zinc, manganese and chromium cations from aqueous solution by a clay mineral10.1016/j.jhazmat.2006.02.001 ↗
21. 1980
22. Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and b-carotene10.1016/j.fct.2004.05.001 ↗
23. FAO/WHO · 2003
24. Effect of cadmium on gap junctional intercellular communication in primary cultures of rat renal proximal tubular cells10.1016/S0024-3205(01)01063-3 ↗
25. Determination of serum proteins by means of the biuret reaction10.1016/S0021-9258(18)57021-6 ↗
26. Use of clay mineral (montmorillonite) for reducing poultry litter leachate toxicity (EC50)10.1016/j.jhazmat.2004.05.024 ↗
27. Cadmium-induced acute hepatic injury is exacerbated in human interleukin-8 transgenic mice10.1006/taap.1999.8877 ↗
28. Identification of a murine locus conveying susceptibility to cadmium-induced forelimb malformations10.1006/geno.1999.6069 ↗
29. Effect of taurine on toxicity of cadmium in rats10.1016/S0300-483X(01)00472-3 ↗
30. Health effects of cadmium exposure – a review of the literature and a risk estimate
31. A simulation study of the removal efficiency of granular activated carbon on cadmium and lead10.1016/j.desal.2006.04.048 ↗
32. Effects of exogenous metallothionein on acute cadmium toxicity in rats10.1385/BTER:104:3:223 ↗
33. Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis10.1016/j.bbrc.2004.11.173 ↗
34. Metallothionein: an intracellular protein to protect against cadmium toxicity10.1146/annurev.pharmtox.39.1.267 ↗
35. Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity10.1006/taap.1995.1227 ↗
36. Acute CdMT injection is not a good model to study chronic Cd nephropathy: comparison of chronic CdCl2 and CdMT exposure with acute CdMT injection in rats10.1006/taap.1998.8506 ↗
37. Susceptibility of MT-null mice to chronic CdCl2-induced nephrotoxicity indicates that renal injury is not mediated by the CdMT complex
38. Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles10.1523/JNEUROSCI.14-10-05844.1994 ↗
39. Prevention of maternal and developmental toxicity in rats via dietary inclusion of common aflatoxin sorbents: potential for hidden risks10.1093/toxsci/41.2.175 ↗
40. Histochemical demonstration of mucin after periodic acid10.1038/158202a0 ↗
41. Induction of hepatic and renal metallothionein synthesis by ferric nitrilotriacetate in mice: the role of MT as an antioxidant10.1016/j.taap.2004.08.014 ↗
42. Mercury impairment of mouse thymocyte survival in vitro: involvement of cellular thiols10.1080/15287390590909706 ↗
43. Free radicals scavenger and antihepatotoxic activity of Rosmarinus10.1055/s-2006-959688 ↗
44. Plasma cadmium-metallothionein, a biological exposure index for cadmium-induced renal dysfunction, based on the mechanism of its action10.1016/S0300-483X(98)00083-3 ↗
45. On the role of metallothionein in cadmium- induced renal toxicity10.1007/978-3-0348-6784-9_72 ↗
46. Toxicological aspects of metallothionein
47. Risk assessment of cadmium toxicity on hepatic and renal tissues of rats10.1006/enrs.1998.3865 ↗
48. Reducing human exposure to aflatoxin through the use of clay: a review10.1080/02652030701567467 ↗
49. Improvement of the argyrophilic proteins of the nucleolar organizer region of the optical level10.1007/BF01676192 ↗
50. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases10.1093/ajcp/28.1.56 ↗
51. An improved procedure for serum creatine phosphokinase determination
52. SAS Institute · 1982
53. A global perspective on cadmium pollution and toxicity in non-occupationally exposed population10.1016/S0378-4274(02)00381-8 ↗
54. Low dose exposure to cadmium and its health effects. Part 3. Toxicity in laboratory animals and cultured cells10.1265/jjh.57.615 ↗
55. Oxidative stress as a mechanism of chronic cadmium induced hepatotoxicity and renal toxicity and protection by antioxidants10.1006/taap.1998.8586 ↗
56. Acute, nontoxic cadmium exposure inhibits pancreatic protease activities in the mouse10.1093/toxsci/53.2.474 ↗
57. Surface geochemistry of the clay minerals10.1073/pnas.96.7.3358 ↗
58. Effect of cadmium and selenium on the antioxidant defense system in rat kidneys10.1016/S0742-8413(97)00063-7 ↗
59. Cadmium
60. Adsorption of trace elements from poultry litter by montmorillonite clay10.1016/j.jhazmat.2005.05.036 ↗
61. Nephrotoxicity and the proximal tubule. Insights from cadmium10.1159/000070241 ↗
62. Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways10.1096/fasebj.13.13.1751 ↗
63. Tietz, N.W., (Ed.), 1987. Fundamentals of Clinical Chemistry, 2nd ed. Saunders, W.B., Co., Philadelphia p. 657.
64. Effect of the flavonoid quercetin on cadmium-induced hepatotoxicity10.1016/j.fct.2008.03.009 ↗
65. Wahlefeld, A.W., (Ed.), 1974. Method of enzymatic analysis. Bergmeyer, H.U., New York, NY, Academic Press, Pp 1831–1835.10.1016/B978-0-12-091304-6.50036-7 ↗
66. A Bayes rule for the symmetric multiple comparison problems10.2307/2286085 ↗
67. Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans10.1080/02652030500111129 ↗
68. Toxicological evaluation and metal bioavailability in pregnant rats following exposure to clay minerals in the diet10.1080/15287390490425777 ↗
69. Adsorption of Pb and Cd by amine-modified zeolite10.1016/j.watres.2005.05.017 ↗