Bioinspired hierarchical CoAl-LDH/MFe2O4(Ni, Zn, Co) as peroxidase mimics for colorimetric detection of glucose

Abstract Novel hierarchically porous CoAl-LDH (layered double hydroxides)/MFe2O4(Ni, Zn, Co) hybrids with excellent peroxidase-like catalytic activity, high selectivity and reusability were first fabricated by using natural cotton as a bio-template. Among them, CoAl-LDH/NiFe2O4 exhibited the best intrinsic peroxidase-like property due to its 3D hierarchically porous structure with more exposed active sites, which could effectively catalyze peroxidase substrate 3,3′,5,5′- tetramethylbenzidine (TMB) in the presence of H2O2 to produce typical blue color reaction. A facile and visual system for glucose detection using glucose oxidase was successfully established, which exhibited a sensitive response to glucose in the range of 25–400 μM with detection limit of 13 μM based on the hydroxyl radical originated from the decomposition of H2O2 by the catalysis of CoAl-LDH/MFe2O4(Ni, Co, Zn) hybrids. This work offered an effective strategy to achieve morphology-controllable hierarchically porous materials and provided a new insight into seeking novel enzyme mimetics with enhanced catalytic activities.