Smart montmorillonite-polypyrrole scaffolds for electro-responsive drug release
Source abstract
Abstract
Abstract Hybrids of montmorillonite (Mt) and polypyrrole (PPy) were prepared by in situ electropolymerization of pyrrole monomer in the dispersion of Mt in the presence of drug molecules (aspirin), and aspirin anions were incorporated into the Mt-PPy hybrids as dopants. The resulting drug loaded Mt-PPy was characterized by field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FT-IR), electrochemical impedance spectroscopy (EIS), and X-ray powder diffractometer (XRD). The Mt-PPy hybrids combined the advantages of Mt (relatively large specific surface area) and electro-responsive feature of PPy, which was applied as an electrically tunable drug release platform. Compared with PPy, the electro-stimulated drug release behaviors were significantly enhanced at the Mt-PPy hybrids, indicating that the proposed electro-responsive hybrids might be a promising candidate for smart and intelligent drug release.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Conducting polymers and applications · Supercapacitor Materials and Fabrication · Electrochemical sensors and biosensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (38)
Show source-provided references
1. A study on sustained release formulations for oral delivery of 5-fluorouracil based on alginate-chitosan/montmorillonite nanocomposite systems10.1016/j.clay.2014.09.004 ↗
2. Theoretical modeling of infrared spectra of aspirin and its deuterated derivative10.1016/S0301-0104(02)00912-6 ↗
3. Controlled transdermal iontophoresis of sulfosalicylic acid from polypyrrole/poly(acrylic acid) hydrogel10.1016/j.ijpharm.2009.07.019 ↗
4. Application of taguchi method to investigate the drug release behavior of poly(acrylamide-co-maleic acid)/montmorillonite nanocomposite hydrogels10.1002/adv.21426 ↗
5. Drug release from electric field-responsive nanoparticles10.1021/nn203430m ↗
6. Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics10.1016/j.biomaterials.2004.09.037 ↗
7. Red light responsive diselenide-containing block copolymer micelles10.1039/C2TB00186A ↗
8. Controlled rupture of magnetic polyelectrolyte microcapsules for drug delivery10.1021/la801138e ↗
9. Montmorillonite as a drug delivery system: intercalation and in vitro release of timolol maleate10.1016/j.ijpharm.2009.03.004 ↗
10. Montmorillonite intercalated with vitamin B1 as drug carrier10.1016/j.clay.2009.06.001 ↗
11. The layered silicate, montmorillonite (MMT) as a drug delivery carrier10.4028/www.scientific.net/KEM.571.111 ↗
12. Palygorskite polypyrrole nanocomposite: a new platform for electrically tunable drug delivery10.1016/j.clay.2014.06.020 ↗
13. Expanded graphite modified with intercalated montmorillonite for the electrochemical determination of catechol10.1016/j.jelechem.2012.01.014 ↗
14. Carvedilol/montmorillonite: processing, characterization and release studies10.1016/j.clay.2010.03.008 ↗
15. New methods of drug delivery10.1126/science.2218494 ↗
16. Release of chlorambucil from poly(N-isopropylacrylamide) hydrogels with β-cyclodextrin moieties10.1002/mabi.200400037 ↗
17. Aluminated mesoporous silica-pillared montmorillonite as acidic catalyst for catalytic cracking10.1016/j.clay.2011.06.003 ↗
18. Synthesis of titania modified silica-pillared clay (SPC) with highly ordered interlayered mesoporous structure for removing toxic metal ion Cr(VI) from aqueous state10.1016/j.apsusc.2013.12.113 ↗
19. Formulations of zero-order, pH-dependent, sustained release matrix systems by ionotropic gelation of alginate-containing mixtures10.3109/03639045.2010.504726 ↗
20. Hyaluronic acid-polypyrrole nanoparticles as pH-responsive theranostics10.1039/C4CC06349J ↗
21. Electroplated porous polypyrrole nanostructures patterned by colloidal lithography for drug-delivery applications10.1039/c2nr30192j ↗
22. Gallic acid-loaded montmorillonite nanostructure as a new controlled release system10.1016/j.clay.2015.10.020 ↗
23. Pressure and microwave sensors/actuators based on smart hydrogel/conductive polymer nanocomposite10.1016/j.snb.2013.08.054 ↗
24. Synthesis and characterization of chlorhexidine acetate drug-montmorillonite intercalates for antibacterial applications10.1016/j.clay.2014.09.010 ↗
25. Polyoxypropylene-montmorillonite nanocomposites for drug-delivery vehicles: preparation and characterization10.1002/app.35609 ↗
26. Electro-responsive macroporous polypyrrole scaffolds for triggered dexamethasone delivery10.1016/j.ejpb.2015.06.018 ↗
27. Nanostructured biocompatible thermal/electrical stimuli-responsive biopolymer-doped polypyrrole for controlled release of chlorpromazine: kinetics studies10.1016/j.ijpharm.2014.06.036 ↗
28. High surface area polypyrrole scaffolds for tunable drug delivery10.1016/j.ijpharm.2013.01.006 ↗
29. pH- and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery10.1039/C4RA09640A ↗
30. Development of a controlled release system for risperidone using polypyrrole: mechanistic studies10.1002/elan.200900401 ↗
31. Conducting polymer nanostructures and their application in biosensors10.1016/j.jcis.2009.09.029 ↗
32. Polypyrrole/conductive mica composites: preparation, characterization, and application in supercapacitor10.1016/j.synthmet.2010.01.018 ↗
33. Self-assembled conducting polypyrrole micro/nanotubes10.1088/0957-4484/13/6/315 ↗
34. Stepwise removal of the copolymer template from mesopores and micropores in SBA-1510.1021/cm049526z ↗
35. Synthesis of titania-pillared montmorillonite via intercalation of titanium alkoxide dissolved in supercritical carbon dioxide10.1039/b404584j ↗
36. Can sonication enhance release from liquid-core capsules with a hydrogel membrane?10.1016/j.jcis.2011.11.038 ↗
37. Simultaneous determination of hydroquinone and catechol at PASA/MWNTs composite film modified glassy carbon electrode10.1016/j.colsurfb.2009.07.044 ↗
38. Preparation and functionality of clay-containing films10.1039/c1jm11479d ↗