Preparation, characterization and application in controlled release of Ibuprofen-loaded Guar Gum/Montmorillonite Bionanocomposites
Source abstract
Abstract
Abstract Neutral guar gum-montmorillonite and cationic guar gum-montmorillonite nanocomposites loaded with ibuprofen were prepared, and their ability to control in vitro release of the drug was presented. These materials exhibited a reduced initial burst release effect and sustained release of up to several hours in a pH 7.4 simulated intestinal fluid. Blank experiments suggested a nanocomposite-mediated action. Improved properties were demonstrated for two different clay minerals: Sodium Wyoming (SWy-2) montmorillonite from the Source Clay Repository and a Portuguese montmorillonite from the Benavila bentonite deposit. The prepared materials were based on abundant, low-cost, natural minerals and plant-extracted biopolymers, and were synthesized using a facile method, thus exhibiting a low environmental impact.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Clay minerals and soil interactions · Therapeutic Uses of Natural Elements · biodegradable polymer synthesis and properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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