journal article·2008-06

Itraconazole–Laponite: Kinetics and mechanism of drug release

Hyun Jung, Hyun-Mi Kim, Young Bin Choy, Seong-Ju Hwang, Jin-Ho Choy

Applied Clay Science· Volume 40· Issue 1-4
Publisher page

Abstract

Abstract A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH = 1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Clay minerals and soil interactions · Layered Double Hydroxides Synthesis and Applications · Mesoporous Materials and Catalysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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