journal article·2025-12-01Open access

A unified normalization framework for dissipated energy in anisotropic aortic tissue under biaxial stretching

Renye Cai, Jinchuan Liu, Jinfeng Cai, Heng Zhang, Tianyu Bo, Ri Chen, Jian Liu, Guanda Yang, Muchao Qu

APL Materials· Volume 13· Issue 12

Abstract

This study investigates the anisotropic mechanical properties and energy dissipation behavior of aortic tissue under biaxial stretching. By introducing the reciprocal value of the self-stretching ratio and the standardization factor, we established a unified framework linking strain-dependent Young’s modulus to energy dissipation in the radial and axial directions. The results suggest different mechanical roles of collagen and elastic fibers in maintaining structural integrity and adaptability under physiological conditions. A novel normalization process was developed to eliminate the influence of modulus variation, enabling precise evaluation of energy dissipation. These findings provide valuable insights into vascular biomechanics and contribute to the understanding of diseases such as atherosclerosis and aneurysms.
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Research context

OpenAlex topics: Elasticity and Material Modeling · Cardiovascular Health and Disease Prevention · Connective tissue disorders research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Automobile and Transportation Engineering, Guangdong Polytechnic Normal University 1 , Guangzhou, Guangdong,

School of Mechatronic Engineering, Guangdong Polytechnic Normal University 2 , 510450 Guangzhou,

Guangdong Provincial Key Laboratory for Processing and Forming of Advanced Metallic Materials, South China University of Technology 3 , Guangzhou 510640,

Institute of Polymer Materials, Friedrich-Alexander-University Erlangen-Nuremberg 4 , Martensstr. 7, 91058 Erlangen,

Funding

Opening Project of Guangdong Provincial Key Laboratory for Processing and Forming of Advanced Metallic Materials · National Natural Science Foundation of China · Guangdong Basic and Applied Basic Research Foundation of China · Key Project in Priority Areas for General Universities, Guangdong Provincial Department of Education

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