Research Update: Interfacing ultrasmall metal nanoclusters with biological systems
Source abstract
Abstract
Metal nanoclusters (NCs), a new type of nanomaterial with unique physicochemical properties, show great potential in many biomedical applications. Understanding their behavior in the complex biological environment is critical not only for designing highly efficient NC-based nanomedicines but also for elucidating the biological impact (e.g., toxicity) of these emerging nanomaterials. In this review, we give an overview of recent progress in exploring interactions of metal NCs with biological systems, including protein adsorption onto NCs, NC interactions with cells, and also the in vivo behavior of NCs. We also discuss the biological responses to the interactions, key parameters defining the interactions, and current challenges in the exploration of NCs in the complex biological environment.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Nanocluster Synthesis and Applications · Advanced Nanomaterials in Catalysis · Gold and Silver Nanoparticles Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Northwestern Polytechnical University 1 Center for Nano Energy Materials, School of Materials Science and Engineering, , Xi’an 710072, China
Karlsruhe Institute of Technology (KIT) 2 Institute of Applied Physics, , 76131 Karlsruhe, Germany
Karlsruhe Institute of Technology (KIT) 3 Institute of Nanotechnology, , 76344 Eggenstein-Leopoldshafen, Germany
Karlsruhe Institute of Technology (KIT) 4 Institute of Toxicology and Genetics, , 76344 Eggenstein-Leopoldshafen, Germany
University of Illinois at Urbana-Champaign 5 Department of Physics, , Urbana, Illinois 61801, USA
Funding
Helmholtz Program STN · National 1000 Young Talent Programme · Deutsche Forschungsgemeinschaft
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