Bionic hydrogel treatments for diabetic wounds

Diabetic wounds are characteristically difficult to heal, have a risk of serious long-term effects, and can lead to amputation and death in severe cases. In addition to routine blood glucose control, dressing is a promising diabetic wound treatment. Bionic hydrogels are novel biomaterials that combine the advantages of biomimetics and hydrogels, resulting in good biocompatibility and water retention and, thus, ideal wound dressing characteristics. A significant amount of research has gone into the pathogenesis of diabetic wounds, which has guided the design of bionic hydrogels with special functions for treating diabetic wounds and supported novel therapeutic interventions. This review provides a detailed overview of bionic hydrogel materials and their construction methods and summarizes bionic hydrogel treatments for diabetic wounds to provide a theoretical basis for future developments.