In-vitro bioassay of electrophoretically deposited hydroxyapatite–zirconia nanocomposite coating on Ti–6Al–7Nb implant
Source abstract
Abstract
Hydroxyapatite–zirconia (HA–ZrO2) nanocomposite coatings were prepared on Ti–6Al–7Nb implant by electrophoretic deposition at constant voltage of 50 V. The influence of zirconia content on the phase transition, morphological evolution, wettability and in vitro cyto-compatibility, together with the bioactivity of the nanostructured coatings was examined. From the X-ray diffractometer patterns, a tangible increase and decrease in the peak intensity and width of the characteristic peaks were observed after subsequent sintering at 1000°C for 1 h under a constant flow of argon gas. The sintered HA and HA–ZrO2 composite coatings showed higher hydrophilicity than the bare substrate. From the in vitro bioassays, surface treatment of Ti67 implant by HA–ZrO2 nanocomposite coating increased the cell response as well as the apatite formability, in simulated body fluid within 5 days of incubation.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Electrophoretic Deposition in Materials Science · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia
Department of Engineering, Center of Advanced Manufacturing and Material Processing, University of Malaya, Kuala Lumpur, Malaysia
Advanced Materials Research Center, Materials Engineering Department, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran
Isfahan Healthcare City, Isfahan, Iran
Institute of Plant Biotechnology and Biology, University of Münster, Münster, Germany
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
Funding
UMRG grant · Research Affairs of Islamic Azad University, Najafabad Branch · UM postgraduate research grant (PPP)
References (55)
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