Synthesis and characterisation of nanocrystalline Ca–Al layered double hydroxide {[Ca 2 Al(OH) 6 ]NO 3 .nH 2 O}: in vitro study
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Abstract
AbstractIn this study, Ca–Al–NO3 layered double hydroxide (LDH) nanoparticles of varying sizes were synthesised by a process involving co-precipitation under hydrothermal condition. This method produces stable homogeneous LDH suspensions under variable hydrothermal treatment conditions with particle size in the range of 7·5–2·5 μm. Layered double hydroxides were characterised by X-ray diffraction, Fourier transform infrared spectroscopy, thermal gravimetric/differential thermal analysis, scanning electron microscopy and transmission electron microscopy (TEM) and nanosizer analyses. By increasing the hydrothermal treatment time, the crystallinity and the particle size of obtained LDH increased. Scanning electron microscopy and TEM observations showed uniform hexagonal flake-like particles with high aspect ratio. Finally, Ca–Al–NO3 LDH did not show any acute cytotoxic effect up to 100 μg mL−1 as measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
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Research context
OpenAlex topics: Layered Double Hydroxides Synthesis and Applications · Magnesium Oxide Properties and Applications · Inorganic Chemistry and Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (23)
Show source-provided references
1. Choy JH · ‘Inorganic layered double hydroxides as nonviral vectors’, Angew. Chem. · 2000 · 22 · 4042
2. 10.1080/1058725000802617610.1080/10587250008026176 ↗
3. Khan AI · ‘Intercalation chemistry of layered double hydroxides: recent developments and applications’, J. Mater. Chem. · 2002 · 12 · 3191
4. Kwak SY · ‘Inorganic delivery vector for intravenous injection’, Biomaterials · 2004 · 25 · 5995
5. 10.1016/j.jconrel.2003.12.02710.1016/j.jconrel.2003.12.027 ↗
6. Choy JH · ‘Layered double hydroxide as an efficient drug reservoir for folate derivatives Biomaterials’, Biomaterials · 2004 · 25 · 3059
7. Braterman PS, Xu ZP, Yarberry F: ‘Handbook of Layered Materials’, 373; 2004, New York, Marcel Dekker.
8. Zhao Y · ‘Preparation of layered double-hydroxide nanomaterials with a uniform crystallite size using a new method involving separate nucleation and aging steps’, Chem. Mater. · 2002 · 14 · 4286
9. Xu ZP · ‘Dispersion and Size Control of Layered Double Hydroxide Nanoparticles in Aqueous Solutions’, J. Phys. Chem. · 2006 · 110 · 16923
10. Tao Q · ‘Synthesis and characterization of layered double hydroxides with a high aspect ratio’, J. Solid State Chem. · 2006 · 179 · 708
11. Oh JM · ‘The effect of synthetic conditions on tailoring the size of hydrotalcite particles Solid State Ionics’, Solid State Ionics · 2002 · 151 · 285
12. Ogawa M · ‘Homogeneous precipitation of uniform hydrotalcite particles’, Langmuir · 2002 · 18 · 4240
13. Adachi-Pagano M · ‘Synthesis of Al-rich hydrotalcite-like compounds by using the urea hydrolysis reaction-control of size and morphology’, J. Mater. Chem. · 2003 · 13 · 1988
14. Kovanda F · ‘Crystallization of synthetic hydrotalcite under hydrothermal conditions’, Appl. Clay Sci. · 2005 · 28 · 101
15. Rojas Delgado R · Influence of MII/MIII ratio in surface-charging behavior of Zn-Al layered double hydroxides’, Appl. Clay Sci. · 2008 · 40 · 23
16. 10.1021/cm010347g10.1021/cm010347g ↗
17. Raki L · ‘Layered double hydroxide-like materials: nanocomposites for use in concrete’, Cem. Concr. Res. · 2004 · 34 · 1717
18. Lopez-Salinas E · ‘Characterization of synthetic hydrocalumite-type [Ca2Al(OH)6]NO3. mH2O: effect of the calcination temperature’, J. Porous Mater. · 1996 · 2 · 291
19. Xu ZP · ‘Hydrothermal synthesis of layered double hydroxides (LDHs) from mixed MgO and Al2O3: LDH formation mechanism’, Chem. Mater. · 2005 · 17 · 1055
20. Albiston L · ‘Rheology and microstructure of aqueous layered double hydroxide dispersions’, J. Mater. Chem. · 1996 · 6 · 871
21. Miyata S · ‘The syntheses of hydrotalcite-like compounds and their structures and phisico-chemical properties I: ‘The systems Mg Z+-A13+-NO3, MgZ+-A13+-C1-, Mg 2 +-A13 +-ClO, Ni 2 +-A13 +-C1- AND Zn 2 +-A13 +-C1-’, Clays Clay Miner. · 1975 · 23 · 369
22. Hickey L · ‘the effects of various hydrothermal treatments on magnesium-aluminium hydrotalcites’, J. Mater. Sci. · 2000 · 11 · 4347
23. Constantino VRL · ‘Basic properties of Mg2+ 1-x Al3+x layered double hydroxides intercalated by carbonates, hydroxide, chloride, and sulfate anions’, Inorg. Chem. · 1995 · 34 · 883