Lipase Enzymes for Sustainable Synthesis of Pharmaceuticals and Chiral Organic Building Blocks
Source abstract
Abstract
Abstract Biocatalysis is a green and sustainable process for synthesizing chiral organic building blocks and active pharmaceutical ingredients (API). United Nations' Sustainable Development Goals 2030 advocates using green, sustainable, recyclable chemicals by industries to reduce environmental pollution. Pharmaceutical companies are adopting biocatalysis technologies for manufacturing chiral active pharmaceutical ingredients. The lipase‐catalyzed kinetic and dynamic‐kinetic resolution method is a pharmaceutically accepted process for manufacturing chiral API. This review describes the reported methods for synthesizing chiral API/KSM (Key Starting Material) molecules using lipase enzymes over the last ten years.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Enzyme Catalysis and Immobilization · Microbial Metabolic Engineering and Bioproduction · Analytical Chemistry and Chromatography
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Medicinal Chemistry and Centre for Marine Therapeutics (CMT) National Institute of Pharmaceutical Education and Research‐Kolkata 168, Maniktala Main Road Kolkata 700054 India
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