Evolution of Rhodamine B into Near‐Infrared Dye by Phototriggered Radical Reaction and Its Application for Lysosome‐Specific Live‐Cell Imaging

A facile process for preparation of near-infrared rhodamine dye by photoirradiation is explored. When a simple rhodamine B bromoacetohydrazide is irradiated with UV light, it can evolve into a near-infrared dye via a phototriggered radical reaction. The dye displays large spectrum shifts in preactivated and activated forms, which allows its use as a fluorescent probe in cell imaging. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.