journal article·2025-08Open access

Microlasers Made Entirely from Edible Substances

Abdur Rehman Anwar, Maruša Mur, Georgia Michailidou, Dimitrios N. Bikiaris, Matjaž Humar

Advanced Optical Materials· Volume 13· Issue 22

Abstract

Abstract Biolasers composed of biological and biocompatible materials are increasingly used in biomedical applications, including cell barcoding and biosensing. However, no studies have focused on creating lasers from edible substances. Here, consumable substances for both the laser cavity and the gain material are systematically explored. Several fluorescent dyes are identified as effective gain materials for lasing. Two types of microcavities are demonstrated: whispering gallery mode and Fabry–Pérot. The edible microlasers are employed as sensors and barcodes. Due to their extremely narrow spectral lines, the microlasers provide exceptional sensitivity to various environmental factors. They are designed to sense sugar concentration, pH, the growth of bacteria, and exposure to too‐high temperatures. Additionally, they encode multiple data bits, such as manufacturer information and expiration dates, while also functioning as physical unclonable functions for anti‐counterfeiting. The microlasers developed in this study are entirely safe for consumption, do not alter the appearance or taste of food, and are environmentally friendly. Unlike traditional barcodes and sensors placed on the packaging, edible lasers can be embedded directly into edible products. They can significantly enhance traceability, security, and freshness monitoring of food and pharmaceuticals as well as non‐edible products and can be employed for environmental monitoring and biomedical applications.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Photonic and Optical Devices · Innovative Microfluidic and Catalytic Techniques Innovation · Nanofabrication and Lithography Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Condensed Matter Physics J. Stefan Institute Jamova 39 Ljubljana SI‐1000 Slovenia

Jožef Stefan International Postgraduate School Jamova 39 Ljubljana SI‐1000 Slovenia

Laboratory of Polymer Chemistry and Technology, Department of Chemistry Aristotle University of Thessaloniki Thessaloniki GR‐54124 Greece

CENN Nanocenter Jamova 39 Ljubljana SI‐1000 Slovenia

Faculty of Mathematics and Physics University of Ljubljana Jadranska 19 Ljubljana SI‐1000 Slovenia

Funding

H2020 Marie Skłodowska-Curie Actions · European Research Council · Human Frontier Science Program

References (57)

Show source-provided references
1. 10.1021/acs.nanolett.5b0249110.1021/acs.nanolett.5b02491 ↗
2. 10.1038/nphoton.2015.12910.1038/nphoton.2015.129 ↗
3. 10.1038/s41566-019-0489-010.1038/s41566-019-0489-0 ↗
4. 10.1021/acsphotonics.2c0161110.1021/acsphotonics.2c01611 ↗
5. 10.1038/s43586-021-00079-210.1038/s43586-021-00079-2 ↗
6. 10.1038/s41377-021-00471-310.1038/s41377-021-00471-3 ↗
7. 10.1002/lpor.20200013510.1002/lpor.202000135 ↗
8. 10.1038/s41566-020-0631-z10.1038/s41566-020-0631-z ↗
9. 10.1002/adom.20190037710.1002/adom.201900377 ↗
10. 10.1088/1361-6463/ab9bbe10.1088/1361-6463/ab9bbe ↗
11. 10.1039/C9SM01610D10.1039/C9SM01610D ↗
12. 10.1039/C6LC00512H10.1039/C6LC00512H ↗
13. 10.1002/adma20130081810.1002/adma201300818 ↗
14. 10.1016/j.orgel.2018.07.02810.1016/j.orgel.2018.07.028 ↗
15. 10.1039/C4LC01171F10.1039/C4LC01171F ↗
16. 10.1002/adom.20160061310.1002/adom.201600613 ↗
17. 10.1016/j.tifs.2019.01.01710.1016/j.tifs.2019.01.017 ↗
18. 10.1016/j.microc.2019.10429510.1016/j.microc.2019.104295 ↗
19. 10.1021/acsami.3c0903510.1021/acsami.3c09035 ↗
20. 10.1038/s41467-019-14066-510.1038/s41467-019-14066-5 ↗
21. 10.1021/acssensors.9b0044010.1021/acssensors.9b00440 ↗
22. 10.1021/acs.biomac.2c0075310.1021/acs.biomac.2c00753 ↗
23. 10.1002/adhm.20170077010.1002/adhm.201700770 ↗
24. 10.1021/acssensors.2c0128010.1021/acssensors.2c01280 ↗
25. 10.1016/S0009-2614(90)87088-910.1016/S0009-2614(90)87088-9 ↗
26. 10.1016/S0301-0104(02)00731-010.1016/S0301-0104(02)00731-0 ↗
27. 10.1016/j.chemphys.2004.08.00610.1016/j.chemphys.2004.08.006 ↗
28. 10.1038/ncomms672210.1038/ncomms6722 ↗
29. 10.1038/nphoton.2011.9910.1038/nphoton.2011.99 ↗
30. 10.1002/adom.20160102210.1002/adom.201601022 ↗
31. 10.1039/C4LC00485J10.1039/C4LC00485J ↗
32. 10.1038/s41377-021-00561-210.1038/s41377-021-00561-2 ↗
33. 10.1364/OPTICA.3.00080910.1364/OPTICA.3.000809 ↗
34. 10.1038/nmeth.122110.1038/nmeth.1221 ↗
35. 10.1533/joti.2006.027110.1533/joti.2006.0271 ↗
36. 10.1006/anbo.1997.040010.1006/anbo.1997.0400 ↗
37. 10.1021/acsami.6b0695810.1021/acsami.6b06958 ↗
38. 10.1039/C9LC01034C10.1039/C9LC01034C ↗
39. 10.1038/s41467-022-28904-610.1038/s41467-022-28904-6 ↗
40. 10.1038/s41467-018-07248-010.1038/s41467-018-07248-0 ↗
41. 10.1364/JOSAB.10.00195510.1364/JOSAB.10.001955 ↗
42. 10.1007/s12596-022-00933-w10.1007/s12596-022-00933-w ↗
43. 10.1016/j.addr.2009.07.01910.1016/j.addr.2009.07.019 ↗
44. 10.1071/SP0400510.1071/SP04005 ↗
45. 10.1016/j.bios.2019.04.04010.1016/j.bios.2019.04.040 ↗
46. 10.1007/s11746-009-1423-210.1007/s11746-009-1423-2 ↗
47. Lu M. · Appl. Phys. Lett. · 2008 · 93 · 11
48. 10.1002/adom.20130045410.1002/adom.201300454 ↗
49. 10.1038/s41467-018-03874-w10.1038/s41467-018-03874-w ↗
50. 10.1007/s10895-019-02471-410.1007/s10895-019-02471-4 ↗
51. 10.1021/acs.analchem.9b0058310.1021/acs.analchem.9b00583 ↗
52. 10.1039/C4LC00872C10.1039/C4LC00872C ↗
53. 10.1093/jn/133.6.190910.1093/jn/133.6.1909 ↗
54. 10.1063/1.493789710.1063/1.4937897 ↗
55. 10.1021/la403220p10.1021/la403220p ↗
56. 10.1016/j.jcis.2020.10.01410.1016/j.jcis.2020.10.014 ↗
57. EFSA ANS Panel · EFSA J. · 2018 · 16