The Impact of Channel Geometry and Flow Regime on Endothelial Orientation and Morphology in Vessel‐on‐Chip (Adv. Mater. Technol. 7/2025)
Source abstract
Abstract
Vessel-on-Chips In article number 2401994, Jaap M.J. den Toonder and co-workers explore how channel geometry and flow conditions affect blood and lymphatic endothelial cell orientation and morphology in vessel-on-chip models. Different flow conditions result in very different cell morphology in channels with circular and rectangular cross-section. Also, endothelial cell orientation induced by flow affects monocyte-endothelium interaction, crucial for understanding immune cell motility.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications
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Affiliations
Microsystems, Department of Mechanical Engineering Eindhoven University of Technology Eindhoven 5612 AJ The Netherlands
Institute for Complex Molecular Systems Eindhoven 5612 AJ The Netherlands
Laboratory for Cell and Tissue Engineering, Department of Biomedical Engineering Eindhoven University of Technology Eindhoven 5612 AJ The Netherlands
References
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