DataVXAdvanced Materials TechnologiesPaper
journal article·2025-03Open access

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea (Adv. Mater. Technol. 6/2025)

Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria

Advanced Materials Technologies· Volume 10· Issue 6
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Source abstract

Abstract

4D Bioprinted Self-Folding Scaffolds In article number 2401210, Riccardo Gottardi, Carmelo DeMaria, and co-workers present the fabrication via extrusion bioprinting of a bilayer scaffold programmed to self-fold after the printing to mimic the human tracheal anatomy. The scaffold is populated by human cells and supports the maturation of healthy cartilage in its outer part. The design of the scaffold was guided by mathematical modeling.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Tracheal and airway disorders

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Affiliations

Research Center “E. Piaggio” University of Pisa Largo Lucio Lazzarino 1 Pisa 56122 Italy

Department of Information Engineering University of Pisa Via Girolamo Caruso 16 Pisa 56122 Italy

Department of Surgery Division of Otolaryngology Children's Hospital of Philadelphia 3401 Civic Center Blvd Philadelphia PA 19104 USA

Department of Bioengineering School of Engineering and Applied Science University of Pennsylvania 210 South 33rd Street Philadelphia PA 19104 USA

Department of Pediatrics Division of Pulmonary Medicine Perelman School of Medicine University of Pennsylvania Philadelphia 19104 USA

Department of Otorhinolaryngology Perelman School of Medicine University of Pennsylvania 3400 Civic Center Blvd Philadelphia PA 19104 USA

Ri.MED Foundation Via Bandiera, 11 Palermo 90133 Italy

References

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