DataVXAdvanced Materials TechnologiesPaper
journal article·2024-08Open access

Dark‐Field Resonance Rayleigh Scattering Biosensor to Monitor Small Molecules and Determine the Secretory Ability of Single Neuron (Adv. Mater. Technol. 15/2024)

Yi Su, Guoguang Rong, Sumin Bian, Pengbo Wang, Lingfei Li, Yun‐Hsuan Chen, Chao Huang, Hongyong Zhang, Mohamad Sawan

Advanced Materials Technologies· Volume 9· Issue 15
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Source abstract

Abstract

Resonance Rayleigh Scattering Accurate monitoring of neurotransmitters and precise characterization of the secretory ability of neurons are essential for effective treatment of neurological diseases. In article number 2301701, Mohamad Sawan and co-workers discover that the binding of small neurotransmitters to aptamers induces a conformational change that alters the effective radius of Au nanoclusters-aptamer complexes. This change can be detected in the resonance Rayleigh scattering intensity.
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Research context

Nanomaterials

OpenAlex topics: Graphene and Nanomaterials Applications · Spectroscopy Techniques in Biomedical and Chemical Research · Gold and Silver Nanoparticles Synthesis and Applications

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Affiliations

CenBRAIN Neurotech Centre of Excellence School of Engineering Westlake University Hangzhou Zhejiang 310030 China

College of Biomedical Engineering & Instrument Science Zhejiang University Hangzhou Zhejiang 310058 China

Department of Neurology Affiliated Hangzhou First People's Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310003 China

Key Laboratory of Systems Health Science of Zhejiang Province School of Life Science Hangzhou Institute for Advanced Study University of Chinese Academy of Science Hangzhou Zhejiang 310024 China

References

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