journal article·2024-06Open access

4D Printing of Bioartificial, Small‐Diameter Vascular Grafts with Human‐Scale Characteristics and Functional Integrity (Adv. Mater. Technol. 12/2024)

Julian Pfarr, Karina Zitta, Lars Hummitzsch, Georg Lutter, Markus Steinfath, Olav Jansen, Sanjay Tiwari, Farhad Haj Mohamad, Philipp Knueppel, Frank Lichte, Anne‐Sophie Mehdorn, Jana Kraas, Katharina Hess, Fred Faendrich, Jochen Cremer, René Rusch, Jannek Grocholl, Martin Albrecht, Rouven Berndt

Advanced Materials Technologies· Volume 9· Issue 12

Abstract

Bioartificial Vascular Grafts In article number 2301785, Rouven Berndt and co-workers develop a 4D bioprinting strategy for the manufacturing of small-diameter, vascular grafts. Accordingly, a bio-ink is synthesized containing a hybrid molecule from sodium alginate and collagen peptide and combined with endothelial progenitor cells. After maturation, the grafts show characteristics similar to those of human veins.
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Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Additive Manufacturing and 3D Printing Technologies · Pickering emulsions and particle stabilization

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Affiliations

Department of Radiology and Neuroradiology University Hospital of Schleswig–Holstein 24105 Kiel Germany

Vascular Research Center University Hospital of Schleswig–Holstein 24105 Kiel Germany

Department of Diagnostic and Interventional Radiology and Nuclear Medicine University Medical Center Hamburg‐Eppendorf 20246 Hamburg Germany

Department of Anesthesiology and Intensive Care Medicine University Hospital of Schleswig–Holstein 24105 Kiel Germany

Clinic of Cardiovascular Surgery University Hospital of Schleswig–Holstein 24105 Kiel Germany

Molecular Imaging North Competence Center (MOIN CC) University Hospital of Schleswig–Holstein 24118 Kiel Germany

Department of Mechanical Engineering Kiel University of Applied Science 24149 Kiel Germany

Anatomical Institute University of Kiel 24118 Kiel Germany

Clinic of General, Abdominal, Thoracic Transplantation and Pediatric Surgery University Hospital of Schleswig–Holstein 24105 Kiel Germany

Department of Pathology University Hospital of Schleswig–Holstein 24105 Kiel Germany

Department for Applied Cell Therapy University Hospital Schleswig–Holstein 24105 Kiel Germany

References

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