journal article·2023-01Open access

Thermomechanical Soft Actuator for Targeted Delivery of Anchoring Drug Deposits to the GI Tract (Adv. Mater. Technol. 2/2023)

Joshua A. Levy, Michael A. Straker, Justin M. Stine, Luke A. Beardslee, Vivian Borbash, Reza Ghodssi

Advanced Materials Technologies· Volume 8· Issue 2

Abstract

Targeted Drug Delivery In article number 2201365, Reza Ghodssi and co-workers present a 3D-printed actuator for capsule-based localized delivery of anchoring drug deposits to the GI tract. A thin-film heating element enables rapid actuation and is readily compatible with currently existing ingestible sensors and electronics to target GI lesions. Firm drug anchoring is achieved via biomimetic barbed microneedles to enable reliable prolonged drug release at target locations in the GI tract.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research

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Affiliations

Department of Materials Science and Engineering University of Maryland College Park MD 20742 USA

Institute for Systems Research University of Maryland College Park MD 20742 USA

Robert E. Fischell Institute for Biomedical Devices University of Maryland College Park MD 20742 USA

Fischell Department of Bioengineering University of Maryland College Park MD 20742 USA

Department of Electrical and Computer Engineering University of Maryland College Park MD 20742 USA

References

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