Microfluidic Devices: High‐Throughput Separation of Microvesicles from Whole Blood Components Using Viscoelastic Fluid (Adv. Mater. Technol. 12/2020)

In article number 2000612, Jeonghun Nam, Chae Seung Lim, and co-workers demonstrate a sheathless, label-free, viscoelastic microfluidic device for separation of submicrometer microvesicles (MVs) from whole blood. This device enables the isolation of platelet-derived microparticles (PDMPs) from diluted whole blood sample without platelet activation. It can be expected that the device can be used as a standard protocol, enabling high-recovery and high-sensitivity isolation of MVs shed from not only blood cells, but also bacteria, viruses, or cancer, for disease diagnosis in clinical settings.