journal article·2023-12Open access

Biolistic Delivery of Photosensitizer‐Loaded Porous Si Carriers for Localized Photodynamic Therapy (Adv. Mater. Technol. 23/2023)

Elina Haimov‐Talmoud, Michal Rosenberg, Sofia Arshavsky‐Graham, Eli Varon, Orit Shefi, Ester Segal

Advanced Materials Technologies· Volume 8· Issue 23

Abstract

Photodynamic Therapy Highly localized photodynamic therapy (PDT) is achieved by biolistic delivery of photosensitizer-loaded porous silicon microparticles directly into solid tumors, as demonstrated by Orit Shefi, Ester Segal, and co-workers in article 2300877. PDT irradiation following the uptake of the released photosensitizer payload induce substantial inhibition of tumor growth in vivo, opening new possibilities for an improved clinical PDT treatment.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Cancer Research and Treatments

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Affiliations

Department of Physics Bar‐Ilan University Ramat‐Gan 5290002 Israel

Faculty of Engineering Bar‐Ilan University Ramat‐Gan 5290002 Israel

Bar‐Ilan Institute of Nanotechnologies and Advanced Materials Bar‐Ilan University Ramat‐Gan 5290002 Israel

Department of Biotechnology and Food Engineering Technion – Israel Institute of Technology Haifa 3200003 Israel

Russell Berrie Nanotechnology Institute Technion – Israel Institute of Technology Haifa 3200003 Israel

References

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