journal article·2016-07

Defined Micropatterning of ECM Protein Adhesive Sites on Alginate Microfibers for Engineering Highly Anisotropic Muscle Cell Bundles

Prarthana Patil, John M. Szymanski, Adam W. Feinberg

Advanced Materials Technologies· Volume 1· Issue 4
Publisher page

Abstract

A process is developed to engineer hydrogel microfibers with precise micropatterning of ECM protein adhesive sites in order to control the adhesion, spreading, and alignment of muscle cells. Uniquely, the ribbon-like microfibers wrap around the cells, aiding in uniaxial alignment and enabling the formation of multifiber bundles to form larger anisotropic skeletal muscle tissue.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Muscle Physiology and Disorders · 3D Printing in Biomedical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Engineering Department of Materials Science and Engineering Carnegie Mellon University Pittsburgh PA 15213 USA

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