journal article·2026-05Open access

A Flexible Piezoelectric Ultrasonic Patch With Low Operating Voltage and Enhanced Safety for Bubble Cavitation

Xingyu Bai, Lihan Yu, Liyun Zhen, Meng Cui, Xuhao Chen, Jingquan Liu, Bin Yang

Advanced Materials Technologies· Volume 11· Issue 9

Abstract

ABSTRACT The ultrasonic cavitation effect plays a critical role in non‐invasive medical treatment. To develop a flexible ultrasonic cavitation patch, it is necessary to enhance the emission intensity of the transducer to reach the threshold sound pressure at low operating voltages, while simultaneously minimizing potential risks to surrounding tissues. This paper presents a piezoelectric ultrasonic micro‐patch with low operating voltage and high safety. The device is fabricated using microfabrication techniques to obtain thin piezoelectric ceramics, which are then embedded in an elastic base layer to ensure optimal adhesion. A ring‐island structure is further designed to integrate both ultrasonic emission and reception functions within a single patch. Sound field simulation and experimental results indicate that, under a driving voltage of 25 Vpp, the emitted ultrasonic intensity reaches 90 kPa, enabling the observation of bubble generation and oscillation in liquids. The mechanical index is only 0.11. To enhance safety, an ultrasonic switch circuit was designed to ensure the temperature remains below 38°C and the spatial‐peak temporal‐average intensity is less than 100 mW/cm 2 . This study contributes significantly to the advancement of wearable ultrasound therapy.
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Research context

OpenAlex topics: Ultrasound and Hyperthermia Applications · Ultrasound and Cavitation Phenomena · Ultrasound Imaging and Elastography

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

National Key Laboratory of Advanced Micro and Nano Manufacture Technology Shanghai Jiao Tong University Shanghai China

School of Integrated Circuits (School of Information Science and Electronic Engineering) Shanghai Jiao Tong University Shanghai China

Funding

National Key Research and Development Program of China · National Natural Science Foundation of China

References (34)

Show source-provided references
1. 10.1016/j.ultsonch.2024.10700510.1016/j.ultsonch.2024.107005 ↗
2. Wang Z. · 2008
3. 10.1016/j.jconrel.2020.06.00810.1016/j.jconrel.2020.06.008 ↗
4. 10.1098/rsfs.2015.002210.1098/rsfs.2015.0022 ↗
5. 10.1186/s13195‐022‐00981‐110.1186/s13195‐022‐00981‐1 ↗
6. 10.1063/1.497385710.1063/1.4973857 ↗
7. 10.1109/TUFFC.2020.300567010.1109/TUFFC.2020.3005670 ↗
8. 10.1007/s40846‐018‐0391‐010.1007/s40846‐018‐0391‐0 ↗
9. 10.1038/s41467‐025‐58075‐z10.1038/s41467‐025‐58075‐z ↗
10. 10.1016/j.biomaterials.2010.09.06010.1016/j.biomaterials.2010.09.060 ↗
11. 10.1016/j.jconrel.2011.01.00610.1016/j.jconrel.2011.01.006 ↗
12. 10.1002/adma.20230006610.1002/adma.202300066 ↗
13. 10.1038/s41378‐024‐00783‐510.1038/s41378‐024‐00783‐5 ↗
14. 10.3390/mi1401012610.3390/mi14010126 ↗
15. 10.1063/5.016196110.1063/5.0161961 ↗
16. 10.1126/sciadv.abg250710.1126/sciadv.abg2507 ↗
17. 10.1016/j.eml.2016.05.01510.1016/j.eml.2016.05.015 ↗
18. 10.1038/s41928‐024‐01271‐410.1038/s41928‐024‐01271‐4 ↗
19. 10.1109/LED.2020.304503710.1109/LED.2020.3045037 ↗
20. 10.1038/s42005‐023‐01361‐310.1038/s42005‐023‐01361‐3 ↗
21. 10.1126/sciadv.ads563410.1126/sciadv.ads5634 ↗
22. 10.1002/adma.20240952810.1002/adma.202409528 ↗
23. 10.1002/adhm.20210078510.1002/adhm.202100785 ↗
24. 10.1002/adfm.20242502510.1002/adfm.202425025 ↗
25. 10.1038/s41551‐024‐01300‐910.1038/s41551‐024‐01300‐9 ↗
26. 10.1021/acsnano.4c0242610.1021/acsnano.4c02426 ↗
27. 10.1088/2631‐7990/ad62c610.1088/2631‐7990/ad62c6 ↗
28. 10.1038/s41467‐023‐37335‐w10.1038/s41467‐023‐37335‐w ↗
29. 10.1063/5.025027210.1063/5.0250272 ↗
30. 10.1021/acsnano.1c1118110.1021/acsnano.1c11181 ↗
31. 10.1063/5.019119110.1063/5.0191191 ↗
32. 10.1038/s41467‐024‐48748‐610.1038/s41467‐024‐48748‐6 ↗
33. 10.1016/j.nanoen.2024.11018810.1016/j.nanoen.2024.110188 ↗
34. 10.1021/acsami.4c1004910.1021/acsami.4c10049 ↗