Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo
Source abstract
Abstract
Abstract 3D objects with integrated electronics are produced using an additive manufacturing approach relying on multiphoton fabrication (direct laser writing, (DLW)). Conducting polymer‐based structures (with micrometer‐millimeter scale features) are printed within exemplar matrices, including an elastomer (polydimethylsiloxane, (PDMS)) have been widely investigated for biomedical applications. The fidelity of the printing process in PDMS is assessed by optical coherence tomography, and the conducting polymer structures are demonstrated to be capable of stimulating mouse brain tissue in vitro. Furthermore, the applicability of the approach to printing structures in vivo is demonstrated in live nematodes (Caenorhabditis elegans). These results highlight the potential for such additive manufacturing approaches to produce next‐generation advanced material technologies, notably integrated electronics for technical and medical applications (e.g., human‐computer interfaces).
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Neuroscience and Neural Engineering · Nonlinear Optical Materials Studies · 3D Printing in Biomedical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry Lancaster University John Creed Avenue Lancaster LA1 4YB UK
Division of Biomedical and Life Sciences Lancaster University Tower Avenue Lancaster LA1 4YQ UK
Department of Electrical Engineering and Electronics University of Liverpool Liverpool L69 3GJ UK
School of Engineering Lancaster University Gillow Avenue Lancaster LA1 4YW UK
School of Chemistry and Biosciences University of Bradford Bradford BD7 1DP UK
NeuDrive Ltd. Daresbury Laboratory Sci‐Tech Keckwick Lane, Daresbury Warrington WA4 4AD UK
The Manufacturing Technology Centre Ansty Business Park Coventry CV7 9JU UK
Lancashire Teaching Hospitals NHS Trust Royal Preston Hospital Sharoe Green Lane Preston PR2 9HT UK
Lancaster Medical School Health Innovation One Sir John Fisher Drive Lancaster University Lancaster LA1 4AT UK
Materials Science Institute Lancaster University Lancaster LA1 4YW UK
Department of Neuroscience Physiology and Pharmacology University College London London WC1E 6BT UK
Centre for Ageing Research Lancaster University Lancaster LA1 4YQ UK
Funding
Biotechnology and Biological Sciences Research Council · Defence Science and Technology Laboratory · Wellcome Trust · Medical Research Council · Mental Health Research UK · Engineering and Physical Sciences Research Council
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