journal article·2019-06

Advances in Reagents Storage and Release in Self‐Contained Point‐of‐Care Devices

Jinqi Deng, Xingyu Jiang

Advanced Materials Technologies· Volume 4· Issue 6
Publisher page

Abstract

Abstract Microfluidics has emerged as a useful material for point‐of‐care testing. However, conventional microfluidic devices rely on multiple steps to complete the detection process, which may not be acceptable for untrained users. The emerging “self‐contained” point‐of‐care devices, with all necessary reagents prestored in, address this limitation. This paper summarizes the recent advances of self‐contained point‐of‐care devices, with emphasis on the approaches for reagents integration and manipulation. Due to the intrinsic similarity and relevance of these approaches in pharmaceutical applications, several examples about drug delivery in vivo are presented. Different approaches are compared and future trends for the development of self‐contained point‐of‐care devices are outlined.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · Innovative Microfluidic and Catalytic Techniques Innovation · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing Engineering Research Center for BioNanotechnology and CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 China

Sino‐Danish College Sino‐Danish Center for Education and Research University of Chinese Academy of Sciences Beijing 100049 China

Department of Biomedical Engineering Southern University of Science and Technology No. 1088 Xueyuan Road, Nanshan District Shenzhen Guangdong 518055 P. R. China

Funding

Chinese Academy of Sciences · Ministry of Science and Technology of the People's Republic of China · National Natural Science Foundation of China

References (100+)

Show source-provided references
1. 10.1016/j.trac.2016.03.01310.1016/j.trac.2016.03.013 ↗
2. 10.1039/C7LC00627F10.1039/C7LC00627F ↗
3. 10.1039/C7LC00815E10.1039/C7LC00815E ↗
4. 10.1016/j.addr.2017.12.01510.1016/j.addr.2017.12.015 ↗
5. 10.1021/acs.analchem.6b0463010.1021/acs.analchem.6b04630 ↗
6. 10.1016/j.bios.2017.04.04410.1016/j.bios.2017.04.044 ↗
7. 10.1016/j.bios.2016.01.02910.1016/j.bios.2016.01.029 ↗
8. 10.3390/mi702003210.3390/mi7020032 ↗
9. 10.1016/j.bios.2015.11.03910.1016/j.bios.2015.11.039 ↗
10. 10.1039/C8AY00864G10.1039/C8AY00864G ↗
11. 10.1002/admt.20170013010.1002/admt.201700130 ↗
12. 10.7150/thno.1867510.7150/thno.18675 ↗
13. 10.1039/C6LC00712K10.1039/C6LC00712K ↗
14. 10.1039/c3cs60118h10.1039/c3cs60118h ↗
15. 10.1038/nm.240810.1038/nm.2408 ↗
16. 10.1021/acs.analchem.7b0128810.1021/acs.analchem.7b01288 ↗
17. 10.1039/C8AN00898A10.1039/C8AN00898A ↗
18. 10.1021/ac503072a10.1021/ac503072a ↗
19. 10.1039/C5LC00609K10.1039/C5LC00609K ↗
20. 10.1021/ac504054u10.1021/ac504054u ↗
21. 10.1039/C5LC00510H10.1039/C5LC00510H ↗
22. 10.1039/C7LC00350A10.1039/C7LC00350A ↗
23. 10.1039/C8LC00471D10.1039/C8LC00471D ↗
24. 10.1063/1.481693410.1063/1.4816934 ↗
25. 10.1016/j.aca.2017.05.03110.1016/j.aca.2017.05.031 ↗
26. 10.1039/C6LC01450J10.1039/C6LC01450J ↗
27. 10.1002/admt.20160026710.1002/admt.201600267 ↗
28. 10.1016/j.bios.2015.09.04910.1016/j.bios.2015.09.049 ↗
29. 10.1002/anie.20141150810.1002/anie.201411508 ↗
30. 10.1021/acs.analchem.7b0317710.1021/acs.analchem.7b03177 ↗
31. 10.1039/C7LC00780A10.1039/C7LC00780A ↗
32. 10.1093/infdis/jiw33010.1093/infdis/jiw330 ↗
33. 10.1039/b921140c10.1039/b921140c ↗
34. 10.1039/C5LC00313J10.1039/C5LC00313J ↗
35. 10.1039/C5LC00871A10.1039/C5LC00871A ↗
36. 10.1021/acs.analchem.7b0383410.1021/acs.analchem.7b03834 ↗
37. 10.1039/C6LC01238H10.1039/C6LC01238H ↗
38. 10.1016/j.bios.2015.01.02710.1016/j.bios.2015.01.027 ↗
39. 10.1016/j.aca.2014.10.01110.1016/j.aca.2014.10.011 ↗
40. 10.1021/acs.analchem.8b0154310.1021/acs.analchem.8b01543 ↗
41. 10.1039/C7LC00138J10.1039/C7LC00138J ↗
42. 10.1016/j.bios.2014.09.02810.1016/j.bios.2014.09.028 ↗
43. 10.1002/adhm.20150017310.1002/adhm.201500173 ↗
44. 10.1016/j.bios.2016.05.07210.1016/j.bios.2016.05.072 ↗
45. 10.1016/j.bios.2015.05.02510.1016/j.bios.2015.05.025 ↗
46. 10.1021/acs.analchem.7b0222210.1021/acs.analchem.7b02222 ↗
47. 10.1021/acsnano.7b0246610.1021/acsnano.7b02466 ↗
48. 10.1002/adma.20150261510.1002/adma.201502615 ↗
49. 10.1016/j.bios.2014.12.04210.1016/j.bios.2014.12.042 ↗
50. 10.1021/acs.analchem.5b0400510.1021/acs.analchem.5b04005 ↗
51. 10.1021/acsami.7b0759010.1021/acsami.7b07590 ↗
52. 10.1016/j.bios.2015.08.00610.1016/j.bios.2015.08.006 ↗
53. 10.1002/asia.20170113010.1002/asia.201701130 ↗
54. 10.1039/C5CC08611F10.1039/C5CC08611F ↗
55. 10.1039/C4LC00348A10.1039/C4LC00348A ↗
56. 10.1016/j.bios.2015.04.09510.1016/j.bios.2015.04.095 ↗
57. 10.1021/acsnano.8b0151510.1021/acsnano.8b01515 ↗
58. 10.1016/j.snb.2016.07.16410.1016/j.snb.2016.07.164 ↗
59. 10.1002/anie.20140948910.1002/anie.201409489 ↗
60. 10.1039/C4LC01370K10.1039/C4LC01370K ↗
61. 10.1021/acsami.5b0679610.1021/acsami.5b06796 ↗
62. 10.1021/ac501433210.1021/ac5014332 ↗
63. 10.1016/j.bios.2015.08.01610.1016/j.bios.2015.08.016 ↗
64. 10.1016/j.snb.2018.07.16810.1016/j.snb.2018.07.168 ↗
65. 10.1039/C7LC01234A10.1039/C7LC01234A ↗
66. 10.1126/sciadv.150164510.1126/sciadv.1501645 ↗
67. 10.1039/C8LC00165K10.1039/C8LC00165K ↗
68. 10.1021/acs.analchem.6b0362410.1021/acs.analchem.6b03624 ↗
69. 10.1039/C7LC00249A10.1039/C7LC00249A ↗
70. 10.1016/j.bios.2017.08.06010.1016/j.bios.2017.08.060 ↗
71. 10.1039/C1LC20565J10.1039/C1LC20565J ↗
72. 10.1126/sciadv.aao486210.1126/sciadv.aao4862 ↗
73. 10.1039/C6LC01485B10.1039/C6LC01485B ↗
74. 10.1016/j.bios.2013.10.00410.1016/j.bios.2013.10.004 ↗
75. 10.1039/C4LC00532E10.1039/C4LC00532E ↗
76. 10.1002/adhm.20160092010.1002/adhm.201600920 ↗
77. 10.1016/j.bios.2017.10.05110.1016/j.bios.2017.10.051 ↗
78. 10.1039/C6LC00806B10.1039/C6LC00806B ↗
79. 10.1063/1.476356010.1063/1.4763560 ↗
80. 10.1021/acsami.7b0553110.1021/acsami.7b05531 ↗
81. 10.1021/acsami.6b0920610.1021/acsami.6b09206 ↗
82. 10.1002/adma.20120318510.1002/adma.201203185 ↗
83. 10.1039/C5LC00276A10.1039/C5LC00276A ↗
84. 10.1016/j.bios.2015.12.09710.1016/j.bios.2015.12.097 ↗
85. 10.1021/acs.analchem.5b0429410.1021/acs.analchem.5b04294 ↗
86. 10.1039/C5LC01136A10.1039/C5LC01136A ↗
87. 10.1021/acsami.7b0971710.1021/acsami.7b09717 ↗
88. 10.1021/acsnano.6b0604010.1021/acsnano.6b06040 ↗
89. Shao K. · ACS Nano · 2014 · 8 · 1181
90. 10.1038/s41467-017-01050-010.1038/s41467-017-01050-0 ↗
91. 10.1021/acsnano.7b0204810.1021/acsnano.7b02048 ↗
92. 10.1002/anie.20150009610.1002/anie.201500096 ↗
93. 10.1002/adma.20150379910.1002/adma.201503799 ↗
94. 10.1002/anie.20130864710.1002/anie.201308647 ↗
95. 10.1039/C5CC03003J10.1039/C5CC03003J ↗
96. 10.1002/adma.20100141710.1002/adma.201001417 ↗
97. 10.1039/C7NR06689A10.1039/C7NR06689A ↗
98. 10.1002/smll.20160310910.1002/smll.201603109 ↗
99. 10.1002/adma.20170014110.1002/adma.201700141 ↗
100. 10.1002/adma.20170231110.1002/adma.201702311 ↗