DataVXAdvanced Materials InterfacesPaper
journal article·2026-01Open access

Antibody‐Functionalized DNA Hydrogels Recognize and Isolate Living Tumor Cells (Adv. Mater. Interfaces 2/2026)

Laura Bourdon, Audrey Cochard, Yannick Tauran, Yoshinobu Sugitani, Yusuke Sato, Masahiro Takinoue, Hiroyuki Fujita, Teruo Fujii, Soo Hyeon Kim, Anthony J. Genot

Advanced Materials Interfaces· Volume 13· Issue 2
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Source abstract

Abstract

DNA Nanotechnology In the Research Article (DOI: 10.1002/admi.202500619), Soo Hyeon Kim and co-workers present a novel strategy using DNA Y-motif nanostar hydrogels and DNA-functionalized antibodies for precise live-cell manipulation. Target cells are labeled with DNA sticky ends that hybridize with DNA Y-motifs, enabling their incorporation and capture within the hydrogel during self-assembly. This method allows parallel isolation, enrichment, and release of target cell types, demonstrated by selective manipulation of cancer cells.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersNanomaterials

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Advanced Biosensing Techniques and Applications · Supramolecular Self-Assembly in Materials

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Affiliations

Institute of Industrial Science The University of Tokyo 4‐6‐1 Komaba, Meguro‐ku Tokyo 153‐8505 Japan

LIMMS CNRS‐Institute of Industrial Science UMI 2820 The University of Tokyo 4‐6‐1 Komaba, Meguro‐ku Tokyo 153‐8505 Japan

Université de Lyon Université Claude Bernard Lyon 1 CNRS Laboratoire des Multimatériaux et Interfaces Villeurbanne F‐69622 France

Department of Intelligent and Control Systems Kyushu Institute of Technology 680‐4 Kawazu, lizuka Fukuoka 820‐8502 Japan

Department of Computer Science Institute of Science Tokyo 4259, Nagatsuta‐cho, Midori‐ku Yokohama Kanagawa 226‐8501 Japan

Department of Life Science and Technology Institute of Science Tokyo 4259 Nagatsuta‐cho, Midori‐ku Yokohama Kanagawa 226‐8501 Japan

Living Systems Materialogy (LiSM) Research Group International Research Frontiers Initiative (IRFI) Tokyo Institute of Technology 4259, Nagatsuta‐cho, Midori‐ku Yokohama Kanagawa 226‐8502 Japan

Canon Medical Systems Corporation 1385 Shimoishigami Otawara Tochigi 324‐8550 Japan

References

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