DataVXAdvanced Materials InterfacesPaper
journal article·2025-10Open access

Astrocyte Interactions With Ti 3 C 2 T x MXene Flakes: Insights Into Viability, Morphology, and Functionality (Adv. Mater. Interfaces 20/2025)

Dimitris Boufidis, Elizabeth N. Krizman, Cybelle M. Smith, Yihan Xie, Raghav Garg, John C. O'Donnell, Flavia Vitale, D. Kacy Cullen

Advanced Materials Interfaces· Volume 12· Issue 20
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Source abstract

Abstract

Ti3C2Tx MXene on Astrocytes This image shows Ti3C2Tx MXene flakes on the astrocyte membrane. Ti3C2Tx MXene is a two-dimensional nanomaterial with promising properties for application in bioelectronics. In this first systematic evaluation of astrocyte–MXene interactions, scanning electron microscopy reveals Ti3C2Tx adhering to astrocytes without causing any evident alteration of the membrane. Alongside viability, morphology, and calcium imaging assays, these findings establish for the first time the biocompatibility of Ti3C2Tx MXene with astrocytes. More details can be found in the Research Article by Flavia Vitale, D. Kacy Cullen, and co-workers (DOI: 10.1002/admi.202500261).
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsBiomaterials

OpenAlex topics: MXene and MAX Phase Materials · Graphene and Nanomaterials Applications · Physical Unclonable Functions (PUFs) and Hardware Security

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Bioengineering University of Pennsylvania Philadelphia Pennsylvania 19104 USA

Center for Neurotrauma, Neurodegeneration & Restoration Corporal Michael J. Crescenz VA Medical Center Philadelphia Pennsylvania 19104 USA

Center for Neuroengineering and Therapeutics University of Pennsylvania Philadelphia Pennsylvania 19104 USA

Department of Neurosurgery University of Pennsylvania Philadelphia Pennsylvania 19104 USA

Department of Neurology University of Pennsylvania Philadelphia Pennsylvania 19104 USA

References

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