journal article·2025-08Open access

Exploring the Role of Stent Strut Geometry in Cellular Behavior: An In Vitro Chip Model to Understand In‐Stent Restenosis (Adv. Mater. Interfaces 16/2025)

Emmie J.D. Schoutens, Juul Verbakel, Heleen M.M. van Beusekom, Jaap M.J. den Toonder, Olaf van der Sluis, Jan de Boer

Advanced Materials Interfaces· Volume 12· Issue 16

Abstract

In-Stent Restenosis In article 2500170, Jan de Boer and co-workers, develop an in-vitro platform mimicking stent strut cross-sectional shapes. This platform was used to study cellular responses, showing differences in cell proliferation and extracellular matrix alignment for smooth versus sharp-cornered shapes. The research highlights the importance of stent design in minimizing in-stent restenosis risk. Art by N. Burghoorn.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Coronary Interventions and Diagnostics · Integrated Circuits and Semiconductor Failure Analysis · Advanced Machining and Optimization Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Microsystems Research Section Department of Mechanical Engineering Eindhoven University of Technology P.O. Box 513 Eindhoven 5600 MB The Netherlands

Institute for Complex Molecular Systems (ICMS) Eindhoven University of Technology Den Dolech 2 Eindhoven 5600 MB The Netherlands

Biointerface Science Research Section Department of Biomedical Engineering Eindhoven University of Technology Eindhoven 5600 MB The Netherlands

Department of Experimental Cardiology Erasmus Medical Centre Rotterdam 3000 CA The Netherlands

Department of Mechanical Engineering Eindhoven University of Technology Eindhoven 5600 MB The Netherlands

References

Reference metadata was not supplied for this record.