Synthesis of Pigmented Parylene Coatings and Control of the Chromatism Based on Chemical Vapor Deposition Copolymerization

Abstract Coloring and identification procedures for medical devices are important to reduce the risks of defective medical devices or incorrect operations and implantations. The study herein reports a novel platform of color pigment‐modified Parylene coatings to fulfill the needs of medical coatings, providing a surface modification route to alter the important property of color for an underlying material and/or device from its original color. Modification with a naphthalimide derivative is employed for the Parylene precursor. The synthesis of the final color Parylene coating is performed based on a vapor‐phase deposition polymerization process, and the coating is conformally coated on a variety of materials regardless of the shape or dimension. Furthermore, control of the color to create a series of color‐changing Parylene coatings is enabled by vapor deposition copolymerization with a second Parylene derivative source, and predictable color tuning from a primary to a secondary and/or tertiary color is achievable in the experiments and shows accordance with color theory. The reported coating platform represents a colored coating tool and is biocompatible for biotechnological applications.