journal article·2022-08Open access

Maximizing the Accessibility in DNA Origami Nanoantenna Plasmonic Hotspots (Adv. Mater. Interfaces 24/2022)

Cindy Close, Kateryna Trofymchuk, Lennart Grabenhorst, Birka Lalkens, Viktorija Glembockyte, Philip Tinnefeld

Advanced Materials Interfaces· Volume 9· Issue 24

Abstract

Trident DNA Origami In article number 2200255, Cindy Close, Philip Tinnefeld, and co-workers demonstrate the development of a Trident DNA origami structure for single-molecule-based plasmonic biosensing. Trident NanoAntennas with Cleared HOtSpots (NACHOS) are compared with previous DNA origami nanoantenna designs and improved hotspot accessibility is demonstrated. Adjusting the size of the cleared hotspot region improves the kinetics of target molecule binding without compromising fluorescence enhancement.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Plasmonic and Surface Plasmon Research · Gold and Silver Nanoparticles Synthesis and Applications

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Affiliations

Department of Chemistry and Center for NanoScience Ludwig‐Maximilians‐Universität München Butenandtstr. 5‐13 81377 Munich Germany

Institut für Halbleitertechnik Laboratory for Emerging Nanometrology LENA TU Braunschweig Langer Kamp 6a/b 38106 Braunschweig Germany

References

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