journal article·2022-08

Wettability‐Based Cell Sorting: Exploring Label‐Free Isolation Strategy for Mixed Primary Glial Cell Population (Adv. Mater. Interfaces 22/2022)

Eunyoung Park, Minseok Lee, Mong Lung Steve Poon, Eunjung Lee, Sung Gap Im, Jennifer H. Shin

Advanced Materials Interfaces· Volume 9· Issue 22
Publisher page

Abstract

Wettability-Based Cell Sorting A wettability-controlled substrate can be used to separate multiple cell types without the need for a complex labeling procedure, as shown in article number 2200388 by Eunyoung Park, Jennifer Shin, and co-workers. Mixed glial brain cells cultured on a hydrophobic substrate spontaneously segregate into substrate-adherent microglia (green-yellow) and spheroidal aggregates of astrocyte/oligodendrocyte progenitor cells (pink-orange). The hydrophobic poly(cyclohexyl methacrylate) (pCHMA) thin-film substrate permits the natural segregation of glial cell subtypes with dissimilar adhesion properties.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research

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Affiliations

Department of Mechanical Engineering Korea Advanced Institute of Science and Technology 291 Daehak‐ro Daejeon 34141 Republic of Korea

Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology 291, Daehak‐ro Daejeon 34141 Republic of Korea

References

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