journal article·2019-05Open access

Osseointegration: Antibacterial Mesoporous Titania Films with Embedded Gentamicin and Surface Modified with Bone Morphogenetic Protein 2 to Promote Osseointegration in Bone Implants (Adv. Mater. Interfaces 9/2019)

Ane Escobar, Nicolás Muzzio, Emerson Coy, Hui Liu, Elisa Bindini, Patrizia Andreozzi, Guocheng Wang, Paula Angelomé, Mihaela Delcea, Marek Grzelczak, Sergio E. Moya

Advanced Materials Interfaces· Volume 6· Issue 9

Abstract

Mesoporous Titania Films (MTFs) are synthesized through the sol-gel technique for gentamicin loading and delivery, and the functionalization of the MTFs surface with human recombinant bone morphogenetic protein 2. This doubly functionalized MTFs have been shown to be effective against S. aureus colonization and the presence of hrBMP-2 enhances MC3T3-E1 pre-osteoblast cell attachment, proliferation and differentiation. More details can be found in article number 1801648 by Ane Escobar, Sergio E. Moya, and co-workers.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Orthopedic Infections and Treatments

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Affiliations

Soft Matter Nanotechnology Laboratory CIC biomaGUNE Paseo de Miramón 182 20014 Donostia‐San Sebastián Spain

NanoBioMedical Center Adam Mickiewicz University Umultowska 85 61–614 Poznan Poland

Research Center for Human Tissues & Organs Degeneration Shenzhen Institute of Advanced Technology Chinese Academy of Science Shenzhen Guangdong 518055 China

Gerencia Química—Centro Atómico Constituyentes Comisión Nacional de Energía Atómica CONICET Avenida General Paz 1499, B1650KNA San Martín Buenos Aires Argentina

Nanostructure Group ZIK HIKE University of Greifswald Fleischmannstraße 42–44 17489 Greifswald Germany

Ikerbasque Basque Foundation for Science 48013 Bilbao Spain

Donostia International Physics Center Paseo de Manuel Lardizabal 4 20018 Donostia‐San Sebastián Spain

References

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