Nanocarriers Tumor Penetration: Bacteria as Nanoparticles Carrier for Enhancing Penetration in a Tumoral Matrix Model (Adv. Mater. Interfaces 11/2020)
Source abstract
Abstract
In article number 1901942 by Alejandro Baeza, María Vallet-Regí, and co-workers, a novel approach based on bacteria as nanoparticles carrier to improve the tumor penetration is proposed. E. coli, as bacteria model, is decorated with mesoporous silica nanoparticles loaded with doxorubicin by click-type reaction. A remarkable improvement in the penetrability in tumoral matrices is achieved, allowing therefore an upgrading in the anti-cancer efficacy of the drug.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cancer Research and Treatments
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Affiliations
Dpto. Química en Ciencias Farmacéuticas Universidad Complutense de Madrid Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n Madrid 28040 Spain
CIBER de Bioingeniería Biomateriales y Nanomedicina CIBER‐BBN Madrid 28040 Spain
Dpto. Materiales y Producción Aeroespacial ETSI Aeronáutica y del Espacio Universidad Politécnica de Madrid Madrid 28040 Spain
Experimental Hematology Lab IIS‐Fundación Jiménez Díaz UAM Madrid 28040 Spain
References
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