Poly(methyl methacrylate): Covalent Functionalization of PMMA Surface with L‐3,4‐Dihydroxyphenylalanine (L‐DOPA) to Enhance its Biocompatibility and Adhesion to Corneal Tissue (Adv. Mater. Interfaces 1/2020)
Source abstract
Abstract
Poly(methyl methacrylate) (PMMA) surface is covalently functionalized with L-3,4-dihydroxyphenylalanine (L-DOPA) to form stable coating that significantly improves the biocompatibility of the PMMA. L-DOPA-functionalized PMMA also preserves the phenotypic characteristics of corneal fibroblast, supporting cellular adhesion, proliferation, and migration, which may lead to better biointegration of the Boston keratoprosthesis, the most commonly implanted artificial cornea for patients with severe corneal diseases. More details can be found in article number 1900767 by James Chodosh, Miguel Gonzalez-Andrades, and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Corneal Surgery and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Massachusetts Eye and Ear – Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School Boston MA 02114 USA
Department of Science Eastern Connecticut State University Willimantic CT 06226 USA
Maimonides Biomedical Research Institute of Cordoba (IMIBIC) Department of Ophthalmology Reina Sofia University Hospital and University of Cordoba Cordoba 14004 Spain
References
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