journal article·2022-12

A Unimolecular System Combining Efficient Inhibition of NDM‐1 by Coordination Interactions with High ROS for Synergistically Tackling Drug‐Resistant Bacteria (Adv. Mater. Interfaces 34/2022)

Meiqi Li, Ling li, Qiong Yuan, Benkai Bao, Yanli Tang

Advanced Materials Interfaces· Volume 9· Issue 34
Publisher page

Abstract

Treating Drug-Resistant Bacteria A unimolecular probe-based synergistic strategy of NDM-1 activity inhibition combined with photodynamic therapy for tackling drug-resistant bacteria is reported in article number 2201329 by Yanli Tang and colleagues. The probe not only effectively inactivates NDM-1 by coordinating with one Zn ion of NDM-1 but also produces the high 1O2, presenting significant synergistic therapy to overcome E. coli-NDM-1 in vitro and in vivo.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Advanced Nanomaterials in Catalysis

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Affiliations

Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an Shaanxi Province 710119 P. R. China

References

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