journal article·2024-01Open access

Nanoscale Confinement of Dip‐Pen Nanolithography Written Phospholipid Structures on CuZr Nanoglasses

Srivatsan K. Vasantham, Evgeniy Boltynjuk, Sree Harsha Nandam, Eider Berganza Eguiarte, Harald Fuchs, Horst Hahn, Michael Hirtz

Advanced Materials Interfaces· Volume 11· Issue 2

Abstract

Abstract Nanoglasses have attracted considerable interest among material scientists due to their novel and surprising properties. However, there is still a significant gap in understanding how nanoglasses interact with biomaterials and their effects on living cells. Previous cell studies have reported indications of possible proliferation effects, but a comprehensive understanding of differentiating nanoglass influences from distinct material or topography effects is yet to be established. In this study, the interaction between nanoglass surfaces and phospholipids, which are fundamental components of cell membranes, is investigated. The findings reveal a unique stabilizing effect exhibited by nanoglasses on structures created using lipid dip‐pen nanolithography, preventing their spreading over the surface (“confinement”). This discovery suggests that nanoglasses can potentially influence the structure of cell membranes, providing a conceivable mechanism for how nanoglasses may impact cell behavior.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Nanofabrication and Lithography Techniques · Force Microscopy Techniques and Applications · Biochemical and Structural Characterization

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Nanotechnology (INT) Karlsruhe Institute of Technology (KIT) Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Karlsruhe Nano Micro Facility (KNMFi) Karlsruhe Institute of Technology (KIT) Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Department of Metallurgical Engineering Indian Institute of Technology (BHU) Varanasi 221005 India

Physical Institute University of Münster Wilhelm‐Klemm‐Straße 10 48149 Münster Germany

Center for Nanotechnology (CeNTech) University of Münster Heisenbergstraße 11 48149 Münster Germany

Chemical, Biological and Materials Engineering The University of Oklahoma 201 Stephenson Pkwy. Norman OK 73019 USA

Funding

Deutsche Forschungsgemeinschaft · Helmholtz-Gemeinschaft

References (47)

Show source-provided references
1. 10.3762/bjnano.4.6110.3762/bjnano.4.61 ↗
2. 10.1016/j.actamat.2017.07.00110.1016/j.actamat.2017.07.001 ↗
3. 10.1016/j.actamat.2020.03.02110.1016/j.actamat.2020.03.021 ↗
4. 10.1016/j.actamat.2011.07.00710.1016/j.actamat.2011.07.007 ↗
5. 10.1002/adfm.20230238610.1002/adfm.202302386 ↗
6. 10.1002/adem.20180040410.1002/adem.201800404 ↗
7. 10.1063/1.10405410.1063/1.104054 ↗
8. 10.1016/j.intermet.2013.08.00310.1016/j.intermet.2013.08.003 ↗
9. 10.1038/srep0779910.1038/srep07799 ↗
10. 10.1039/c3tb20153h10.1039/c3tb20153h ↗
11. 10.3389/fbioe.2022.100296710.3389/fbioe.2022.1002967 ↗
12. 10.1016/j.actbio.2018.09.05910.1016/j.actbio.2018.09.059 ↗
13. 10.1002/smll.20100151310.1002/smll.201001513 ↗
14. 10.1002/adma.20070142810.1002/adma.200701428 ↗
15. 10.1002/adfm.20120091410.1002/adfm.201200914 ↗
16. 10.1039/D2TB01875F10.1039/D2TB01875F ↗
17. 10.1016/j.bioactmat.2021.11.02410.1016/j.bioactmat.2021.11.024 ↗
18. S.Cao Q.Yuan 2022.10.1155/2022/6453499 ↗
19. 10.1016/j.bbamem.2008.01.01510.1016/j.bbamem.2008.01.015 ↗
20. 10.3390/membranes1302015110.3390/membranes13020151 ↗
21. 10.1126/science.283.5402.66110.1126/science.283.5402.661 ↗
22. 10.1002/smll.20190056410.1002/smll.201900564 ↗
23. 10.1002/smll.20060043110.1002/smll.200600431 ↗
24. 10.1038/ncomms359110.1038/ncomms3591 ↗
25. 10.1002/smll.20220559010.1002/smll.202205590 ↗
26. 10.1016/j.biomaterials.2012.02.02310.1016/j.biomaterials.2012.02.023 ↗
27. 10.1002/smll.20080094910.1002/smll.200800949 ↗
28. 10.1002/adma.20200849310.1002/adma.202008493 ↗
29. 10.1039/D1NR01133B10.1039/D1NR01133B ↗
30. 10.1039/C6NR04615K10.1039/C6NR04615K ↗
31. 10.3390/molecules2512276810.3390/molecules25122768 ↗
32. 10.1088/0960-1317/26/2/02501610.1088/0960-1317/26/2/025016 ↗
33. 10.3390/biomimetics601000310.3390/biomimetics6010003 ↗
34. 10.1021/la202703j10.1021/la202703j ↗
35. 10.1021/acsnano.6b0735210.1021/acsnano.6b07352 ↗
36. 10.1039/b704827k10.1039/b704827k ↗
37. Gözen I. · 2015
38. 10.1002/smll.20080094910.1002/smll.200800949 ↗
39. 10.1021/acs.langmuir.6b0327610.1021/acs.langmuir.6b03276 ↗
40. 10.35848/1347-4065/ab918c10.35848/1347-4065/ab918c ↗
41. 10.1002/admi.20200211710.1002/admi.202002117 ↗
42. 10.1038/srep1255010.1038/srep12550 ↗
43. 10.1021/ar600019r10.1021/ar600019r ↗
44. 10.1016/j.bbamem.2020.18334710.1016/j.bbamem.2020.183347 ↗
45. 10.1002/smll.20160154910.1002/smll.201601549 ↗
46. 10.1016/S0006-3495(02)75273-910.1016/S0006-3495(02)75273-9 ↗
47. 10.1063/1.243241010.1063/1.2432410 ↗