journal article·2025-02Open access

Why Biopolymer Microgels with Dynamically Switchable Properties Would be a Great Tool‐Box for the Cultivation of Stem Cells

Berna Özkale, Oliver Lieleg

Advanced Materials Interfaces· Volume 12· Issue 4

Abstract

Abstract In this short perspective article, it is asked why – different from their macroscopic bulk counterparts – biopolymer‐based microgels with dynamically switchable mechanical properties are basically non‐existent. The article pinpoints why such dynamic control over the viscoelasticity of microgels would be desirable for the encapsulation of stem cells, how switchable mechanical properties may be achievable in biopolymer‐based microgel systems, and what pitfalls and issues need to be addressed to realize such a complex, engineered microenvironment for cells.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Cellular Mechanics and Interactions · Hydrogels: synthesis, properties, applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Microrobotic Bioengineering Lab (MRBL) Department of Electrical Engineering School of Computation, Information and Technology Technical University of Munich Hans‐Piloty‐Straße 1 85748 Garching Germany

Munich Institute of Biomedical Engineering Technical University of Munich Boltzmannstraße 11 85748 Garching Germany

Department of Materials Engineering School of Engineering and Design Technical University of Munich Boltzmannstraße 15 85748 Garching Germany

Center for Protein Assemblies Technical University of Munich Ernst‐Otto‐Fischer Str. 8 85748 Garching Germany

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