DataVXAdvanced Materials InterfacesPaper
journal article·2023-04Open access

Ferromagnetic Cytocompatible Glass‐Ceramic Porous Microspheres for Magnetic Hyperthermia Applications

Jesús Molinar‐Díaz, John Luke Woodliffe, Benjamin Milborne, Lauren Murrell, Md Towhidul Islam, Elisabeth Steer, Nicola Weston, Nicola A. Morley, Paul D. Brown, Ifty Ahmed

Advanced Materials Interfaces· Volume 10· Issue 11
Publisher pageOpen full text
Source abstract

Abstract

Abstract Highly porous, ferromagnetic glass‐ceramic P40‐Fe3O4 microspheres (125–212 µm) with enhanced cytocompatibility have been manufactured for the first time via a facile, rapid, single‐stage flame spheroidization process. Dispersions of Fe3O4 and Ca2Fe2O5 domains (≈10 µm) embedded within P40 (40P2O5‐16CaO‐24MgO‐20Na2O in mol%) phosphate‐based glass matrices show evidence for remanent magnetization (0.2 Am2 kg−1) and provide for controlled induction heating to a constant level of 41.9 °C, making these materials highly appropriate for localized magnetic hyperthermia applications. Complementary, cytocompatibility investigations confirm the suitability of P40‐Fe3O4 porous microspheres for biomedical applications. It is suggested that the flame‐spheroidization process opens up new opportunities for the development of innovative synergistic biomaterials, toward bone‐tissue regenerative applications.
Source: crossref · Quality: baseline

Research context

Ceramics & glassesBiomaterials

OpenAlex topics: Bone Tissue Engineering Materials · Pickering emulsions and particle stabilization · Cellular and Composite Structures

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Advanced Materials Research Group Faculty of Engineering University of Nottingham University Park Nottingham NG7 2RD UK

Nanoscale and Microscale Research Centre University of Nottingham University Park Nottingham NG7 2RD UK

Department of Materials Science and Engineering University of Sheffield Sheffield S1 3JD UK

References (62)

Show source-provided references
1. 10.3322/caac.2166010.3322/caac.21660 ↗
2. 10.1002/advs.20210267810.1002/advs.202102678 ↗
3. 10.1038/s41392-021-00572-w10.1038/s41392-021-00572-w ↗
4. 10.1038/s41392-017-0004-310.1038/s41392-017-0004-3 ↗
5. Lin B. · Front. Oncol. · 2021 · 11
6. 10.1038/nrd400310.1038/nrd4003 ↗
7. 10.1007/s11051-020-05045-910.1007/s11051-020-05045-9 ↗
8. 10.1007/s42114-021-00373-310.1007/s42114-021-00373-3 ↗
9. 10.3109/02656736.2013.83281510.3109/02656736.2013.832815 ↗
10. 10.3389/fphar.2018.0083110.3389/fphar.2018.00831 ↗
11. 10.7150/thno.4080510.7150/thno.40805 ↗
12. 10.1107/S160057671500890010.1107/S1600576715008900 ↗
13. 10.1038/srep2462910.1038/srep24629 ↗
14. 10.7150/thno.5751110.7150/thno.57511 ↗
15. 10.1016/j.biomaterials.2015.11.02310.1016/j.biomaterials.2015.11.023 ↗
16. 10.1080/23746149.2016.125457010.1080/23746149.2016.1254570 ↗
17. 10.3109/0265673100374574010.3109/02656731003745740 ↗
18. 10.1080/02656736.2018.143086710.1080/02656736.2018.1430867 ↗
19. 10.1007/s10147-011-0217-310.1007/s10147-011-0217-3 ↗
20. 10.1002/jbm.a.3088910.1002/jbm.a.30889 ↗
21. 10.1016/j.msec.2019.01.03810.1016/j.msec.2019.01.038 ↗
22. 10.1038/s41598-022-07062-110.1038/s41598-022-07062-1 ↗
23. 10.1080/0265673011011671310.1080/02656730110116713 ↗
24. 10.3390/nano1111278610.3390/nano11112786 ↗
25. 10.1109/LMAG.2018.287903410.1109/LMAG.2018.2879034 ↗
26. 10.1021/acsami.8b1845110.1021/acsami.8b18451 ↗
27. 10.2307/357587410.2307/3575874 ↗
28. 10.1016/j.actbio.2018.11.01310.1016/j.actbio.2018.11.013 ↗
29. 10.3389/fcell.2021.64378110.3389/fcell.2021.643781 ↗
30. 10.1111/jace.1786110.1111/jace.17861 ↗
31. 10.1016/j.actbio.2011.03.01610.1016/j.actbio.2011.03.016 ↗
32. 10.1177/204173141771917010.1177/2041731417719170 ↗
33. 10.1515/bglass-2019-001310.1515/bglass-2019-0013 ↗
34. Cai Y. · Int. J. Nanomed. · 2013 · 8 · 1111
35. 10.1016/j.ijpharm.2018.06.01510.1016/j.ijpharm.2018.06.015 ↗
36. 10.1177/0885328221105929410.1177/08853282211059294 ↗
37. 10.3390/ma705358810.3390/ma7053588 ↗
38. 10.1016/j.inoche.2014.11.01310.1016/j.inoche.2014.11.013 ↗
39. 10.1002/ces2.1001310.1002/ces2.10013 ↗
40. 10.1016/j.jmatprotec.2007.12.08110.1016/j.jmatprotec.2007.12.081 ↗
41. 10.1038/srep3914010.1038/srep39140 ↗
42. 10.1016/j.actbio.2018.03.04010.1016/j.actbio.2018.03.040 ↗
43. 10.1007/s40204-014-0033-810.1007/s40204-014-0033-8 ↗
44. 10.1039/D0MA00564A10.1039/D0MA00564A ↗
45. 10.1016/j.msec.2020.11166810.1016/j.msec.2020.111668 ↗
46. 10.1016/j.pbiomolbio.2017.10.00110.1016/j.pbiomolbio.2017.10.001 ↗
47. 10.1021/acsami.8b0526710.1021/acsami.8b05267 ↗
48. 10.1016/j.physb.2016.01.02910.1016/j.physb.2016.01.029 ↗
49. 10.1016/j.mtbio.2021.10010010.1016/j.mtbio.2021.100100 ↗
50. 10.3389/fmats.2021.63801910.3389/fmats.2021.638019 ↗
51. 10.1016/j.jmmm.2006.10.115610.1016/j.jmmm.2006.10.1156 ↗
52. 10.1016/j.physb.2020.41262710.1016/j.physb.2020.412627 ↗
53. 10.1016/j.addr.2011.03.00810.1016/j.addr.2011.03.008 ↗
54. 10.1021/ja061285410.1021/ja0612854 ↗
55. 10.3390/ma1210157510.3390/ma12101575 ↗
56. 10.1021/acsami.9b0460310.1021/acsami.9b04603 ↗
57. 10.1016/j.bioactmat.2021.03.00610.1016/j.bioactmat.2021.03.006 ↗
58. 10.3390/polym1405088810.3390/polym14050888 ↗
59. 10.1016/j.actbio.2021.09.03410.1016/j.actbio.2021.09.034 ↗
60. 10.1089/ten.tea.2018.007110.1089/ten.tea.2018.0071 ↗
61. 10.3389/fphar.2020.0057310.3389/fphar.2020.00573 ↗
62. 10.1002/adfm.20190707110.1002/adfm.201907071 ↗