journal article·2020-04Open access

Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020)

Wooram Um, Hyewon Ko, Dong Gil You, Seungho Lim, Gijung Kwak, Man Kyu Shim, Suah Yang, Jeongjin Lee, Yeari Song, Kwangmeyung Kim, Jae Hyung Park

Advanced Materials· Volume 32· Issue 16

Abstract

In article number 1907953, Jae Hyung Park and co-workers present the potential of necroptosis-inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage-associated molecular patterns and tumor-associated antigens by inducing cell membrane rupture, facilitating efficient maturation of the dendritic cell for antitumor immune response.
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Research context

OpenAlex topics: Extracellular vesicles in disease

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Affiliations

Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences & Technology (SAIHST) Sungkyunkwan University Seoul 06351 Republic of Korea

School of Chemical Engineering College of Engineering Sungkyunkwan University Suwon 16419 Republic of Korea

Center for Theragnosis Biomedical Research Institute Korea Institute of Science and Technology (KIST) Seoul 02792 Republic of Korea

KU‐KIST Graduate School of Converging Science and Technology Korea University Seoul 02841 Republic of Korea

Biomedical Institute for Convergence at SKKU (BICS) Sungkyunkwan University Suwon 16419 Republic of Korea

References

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