Spinal‐Cord Injury Treatment: Effective Modulation of CNS Inhibitory Microenvironment using Bioinspired Hybrid‐Nanoscaffold‐Based Therapeutic Interventions (Adv. Mater. 43/2020)
Source abstract
Abstract
Current treatment of central nervous system (CNS) injuries has been hampered by the neuroinhibitory microenvironment. In article number 2002578, Jae K. Lee, Ki-Bum Lee, and co-workers develop a method to effectively treat CNS injuries by delivering anti-inflammatory drugs in vivo and providing a permissive neural matrix using biodegradable nanoscaffolds. Implantation of drug-loaded nanoscaffolds to spinal-cord injury sites reduces macrophage infiltration, suppresses fibrotic scarring, and thereby promotes functional recovery.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nerve injury and regeneration · Graphene and Nanomaterials Applications · Mesenchymal stem cell research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry and Chemical Biology Rutgers The State University of New Jersey 123 Bevier Road Piscataway NJ 08854 USA
Miami Project to Cure Paralysis Department of Neurological Surgery University of Miami School of Medicine 1095 NW 14th Terrace, LPLC 4–19 Miami FL 33136 USA
References
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