journal article·2020-10Open access

Helical Peptide Nanofibers: Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8+ T‐Cell Responses (Adv. Mater. 39/2020)

Chelsea N. Fries, Yaoying Wu, Sean H. Kelly, Michelle Wolf, Nicole L. Votaw, Stefan Zauscher, Joel H. Collier

Advanced Materials· Volume 32· Issue 39

Abstract

In nanofibers composed of self-assembling helical peptides, “capping” peptides can limit fiber growth and influence the character of immune responses raised by the materials. In article number 2003310, Joel H. Collier and co-workers design short peptides such that they self-assemble into immunologically active helical nanofibers. The lengths of these fibers, tailorable by the incorporation of structure-modifying peptides within the assemblies, influence the character of the immune responses they elicit. Image Credit: Chelsea Fries and Joel Collier.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Polydiacetylene-based materials and applications · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Engineering 1316 FCIEMAS 101 Science Dr Durham NC 27708 USA

Department of Mechanical Engineering and Materials Science 3385 FCIEMAS 101 Science Dr Durham NC 27708 USA

Department of Chemistry 3385 FCIEMAS 101 Science Dr Durham NC 27708 USA

Department of Immunology 1316 FCIEMAS 101 Science Dr Durham NC 27708 USA

References

Reference metadata was not supplied for this record.