Bone Healing: In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing (Adv. Mater. 8/2020)
Source abstract
Abstract
In article number 1906022, Shyni Varghese and co-workers describe the application of a designer biomaterial “bandage” at the site of a bone injury to sequester and localize innate pro-healing signaling molecules that promote vascularization and healing. The biomaterial-assisted sequestration of adenosine leverages the transient surge of extracellular adenosine following injury to prolong local adenosine signaling, offering a versatile solution to utilizing adenosine as a potential therapeutic for tissue repair.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Tissue Engineering and Regenerative Medicine
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Orthopaedic Surgery Duke University School of Medicine Durham NC 27710 USA
Department of Mechanical Engineering and Materials Science Duke University Durham NC 27710 USA
Duke Molecular Physiology Institute Durham NC 27701 USA
Department of Biomedical Engineering Duke University Durham NC 27710 USA
References
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